VGX-1027 (Git-27) - Moligand™, 10mM in DMSO , CAS No.6501-72-0

CAS: 6501-72-0 Cat. No.: V425294 Molecular Weight: 205.21 EC Number: 636-241-9 PubChem CID: 10798271
AVAILABLE TO ORDER
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
Synonyms
VGX-1027|6501-72-0|GIT 27|4,5-DIHYDRO-3-PHENYL-5-ISOXAZOLEACETIC ACID|git-27|zenuzolac|2-(3-phenyl-4,5-dihydro-1,2-oxazol-5-yl)acetic Acid|2-(3-phenyl-4,5-dihydroisoxazol-5-yl)acetic acid|GIT-027|VGX1027|VGX 1027|GLS1027|GLS-1027|GIT27|AKT814N13R|(3-PHENY
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
Size
Status
Price
Qty
1ml
V425294-1ml
1

$114.90

$167.90
Save $53.00 (31.57%)
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Why this grade

Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Specifications

Synonyms
VGX-1027 | 6501-72-0 | GIT 27 | 4, 5-DIHYDRO-3-PHENYL-5-ISOXAZOLEACETIC ACID | git-27 | zenuzolac | 2-(3-phenyl-4, 5-dihydro-1, 2-oxazol-5-yl)acetic Acid | 2-(3-phenyl-4, 5-dihydroisoxazol-5-yl)acetic acid | GIT-027 | VGX1027 | VGX 1027 | GLS1027 | GLS-1027 | GIT27 | AKT814N13R | (3-PHENY
Specifications & Purity
Moligand™, 10mM in DMSO
Biochemical and Physiological Mechanisms
Immunomodulatory agent. TLR4 inhibitor. TLR4 and TLR 2/6 signaling pathway modulator. Inhibits inflammatory antigen presentation. Inhibits IL1-β, IL-10, IFN-γ and TNF-α secretion. Shows anti-inflammatory effects in vivo. Orally active.
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Product Properties
ALogP1.3
Names and Identifiers
Pubchem Sid528767622
Canonical SmilesC1C(ON=C1C2=CC=CC=C2)CC(=O)O
IUPAC Name2-(3-phenyl-4,5-dihydro-1,2-oxazol-5-yl)acetic acid
InChIKeyMUFJHYRCIHHATF-UHFFFAOYSA-N
INCHI1S/C11H11NO3/c13-11(14)7-9-6-10(12-15-9)8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H,13,14)
Isomeric SMILES C1C(ON=C1C2=CC=CC=C2)CC(=O)O
PubChem CID 10798271
Molecular Weight 205.21

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClassBenzene and substituted derivatives
SubclassNot available
Intermediate Tree Nodes Not available
Direct ParentBenzene and substituted derivatives
Alternative Parents Isoxazolines  Oxacyclic compounds  Monocarboxylic acids and derivatives  Carboxylic acids  Azacyclic compounds  Organonitrogen compounds  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents Monocyclic benzene moiety - Isoxazoline - Carboxylic acid derivative - Carboxylic acid - Oxacycle - Azacycle - Organoheterocyclic compound - Monocarboxylic acid or derivatives - Organic nitrogen compound - Organonitrogen compound - Organooxygen compound - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Carbonyl group - Aromatic heteromonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as benzene and substituted derivatives. These are aromatic compounds containing one monocyclic ring system consisting of benzene.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
ARSA Tbio Cerebroside-sulfatase (655 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HEK293 (82097 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FEN1 Tchem Flap endonuclease 1 (12055 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GCN5 Histone acetyltransferase GCN5 (89 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
pfk 6-phospho-1-fructokinase (7870 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

1 results found

Lot NumberCertificate TypeDateItem
L2201201Certificate of AnalysisAug 13, 2026 V425294
Chemical and Physical Properties
SensitivityAir Sensitive,Heat Sensitive
Melt Point(°C)157.0 to 161.0 °C
Molecular Weight205.210 g/mol
XLogP31.300
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Exact Mass205.074 Da
Monoisotopic Mass205.074 Da
Topological Polar Surface Area58.900 Ų
Heavy Atom Count15
Formal Charge0
Complexity269.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Solution Calculators
Reviews

Customer Reviews

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