2,2'-Dithiobis(5-nitropyridine)(DTNP) - ≥96%, used for as cysteine-activating reagent to study the NMR of G protein-coupled receptors; in the deprotection assays for protected selenocysteine-containing peptides; for deprotecting p-methoxybenzyl groups and

CAS: 2127-10-8 Cat. No.: D579178 分子式: C₁₀H₆N₄O₄S₂ 分子量: 310.31 Beilstein Registry Number: 305413 EC番号: 218-344-7

GRADE & PURITY ≥96%

Synonyms

DTNP | InChI=1/C10H6N4O4S2/c15-13(16)7-1-3-9(11-5-7)19-20-10-4-2-8(6-12-10)14(17)18/h1-6 | Pyridine,2'-dithiobis[5-nitro- | NSC677436 | NSC-677436 | 2,2'-Dithiobis(5-nitropyridine), 96% | NSC 149336 | 2,2'-disulfanediylbis(5-nitropyridine) | 5,5'-Dinitro-

Storage

Room temperature,Desiccated

Shipped In

Normal

概要

2,2′-Dithiobis(5-nitropyridine) is an aromatic disulphide.

Specifications

同義語

DTNP | InChI=1/C10H6N4O4S2/c15-13(16)7-1-3-9(11-5-7)19-20-10-4-2-8(6-12-10)14(17)18/h1-6 | Pyridine,2'-dithiobis[5-nitro- | NSC677436 | NSC-677436 | 2,2'-Dithiobis(5-nitropyridine), 96% | NSC 149336 | 2,2'-disulfanediylbis(5-nitropyridine) | 5,5'-Dinitro-

仕様と純度

≥96%

申し込み

as cysteine-activating reagent to study the NMR of G protein-coupled receptors; in the deprotection assays for protected selenocysteine-containing peptides; for deprotecting p-methoxybenzyl groups and acetamidomethyl groups from the side-chains of cystein

保管条件

Room temperature,Desiccated

入荷

Normal

純度

≥96%

名前と識別子

• パブケム・シド: 488182250
• パブケム・シド・ウル: https://pubchem.ncbi.nlm.nih.gov/substance/488182250
• カノニカル・スマイル: C1=CC(=NC=C1[N+](=O)[O-])SSC2=NC=C(C=C2)[N+](=O)[O-]
• IUPAC Name: 5-nitro-2-[(5-nitropyridin-2-yl)disulfanyl]pyridine
• InChIKey: ROUFCTKIILEETD-UHFFFAOYSA-N
• INCHI: 1S/C10H6N4O4S2/c15-13(16)7-1-3-9(11-5-7)19-20-10-4-2-8(6-12-10)14(17)18/h1-6H
• 異性体SMILES: C1=CC(=NC=C1[N+](=O)[O-])SSC2=NC=C(C=C2)[N+](=O)[O-]
• WGKドイツ: 3
• RTECS: UT2964000
• 分子量: 310.31
• Beilstein: 305413
• Reaxy-Rn: 305413
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=305413&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic 1,3-dipolar compounds
    • 分類 Allyl-type 1,3-dipolar organic compounds
      • Subclass Organic nitro compounds
        • Level5 C-nitro compounds
          • Level6 Nitroaromatic compounds

• Kingdom: Organic compounds
• Superclass: Organic 1,3-dipolar compounds
• 分類: Allyl-type 1,3-dipolar organic compounds
• Subclass: Organic nitro compounds
• Intermediate Tree Nodes: C-nitro compounds
• Direct Parent: Nitroaromatic compounds
• Alternative Parents: Pyridines and derivatives Heteroaromatic compounds Organic disulfides Sulfenyl compounds Propargyl-type 1,3-dipolar organic compounds Organic oxoazanium compounds Azacyclic compounds Organopnictogen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Nitroaromatic compound - Pyridine - Heteroaromatic compound - Organic disulfide - Organic oxoazanium - Sulfenyl compound - Propargyl-type 1,3-dipolar organic compound - Azacycle - Organoheterocyclic compound - Organic nitrogen compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organosulfur compound - Organonitrogen compound - Organic oxygen compound - Aromatic heteromonocyclic compound
• 説明: This compound belongs to the class of organic compounds known as nitroaromatic compounds. These are c-nitro compounds where the nitro group is C-substituted with an aromatic group.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

関連ターゲット（人間）

TRPV1 Tclin Vanilloid receptor (8273 Activities)

Discover Target: TRPV1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TRPV4 Tchem Transient receptor potential cation channel subfamily V member 4 (774 Activities)

Discover Target: TRPV4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TRPV3 Tchem Transient receptor potential cation channel subfamily V member 3 (542 Activities)

Discover Target: TRPV3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TRPM2 Tchem Transient receptor potential cation channel subfamily M member 2 (348 Activities)

Discover Target: TRPM2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TRPC5 Tchem Short transient receptor potential channel 5 (300 Activities)

Discover Target: TRPC5

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

関連ターゲット（非人間）

Human immunodeficiency virus 1 (70413 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

作用メカニズム

化学的性質と物理的性質

• 融点（°C）: 155°C
• 分子量: 310.300 g/mol
• XLogP3: 2.200
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 3
• Exact Mass: 309.983 Da
• Monoisotopic Mass: 309.983 Da
• Topological Polar Surface Area: 168.000 Ų
• Heavy Atom Count: 20
• Formal Charge: 0
• Complexity: 328.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

よくある質問

What is the purity of this product?

This product is supplied at ≥96% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store in a cool place, desiccated. Keep the container tightly closed with desiccant — the material is moisture-sensitive.

How is this product shipped?

This product ships under standard ambient conditions. No temperature-controlled packaging is required.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 2127-10-8, the molecular formula is C10H6N4O4S2, and the molecular weight is 310.31 g/mol. InChIKey ROUFCTKIILEETD-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.