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A 77-01 - ≥98% , CAS No.607737-87-1

CAS: 607737-87-1 Cat. No.: A288900 分子式: C18H14N4 分子量: 286.33
COA
A 77-01 - ≥98% CAS No(607737-87-1) A288900 by Aladdin Scientific
注文可能
GRADE & PURITY ≥98%
Synonyms
A 77-01 | A-77-01 | A77-01 | AKOS026750350 | DTXSID80440480 | E98766 | NCGC00379015-02 | BCP13726 | EX-A2200 | MS-24090 | C18H14N4 | SCHEMBL17559240 | 4-[3-(6-Methyl-pyridin-2-yl)-1H-pyrazol-4-yl]-quinoline | 4-[3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl]qu
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
★
Size
USA
ドイツ (EU)*
Price
Qty
5mg
A288900-5mg
3 在庫あり
—

$150.90

$226.90
保存 $76.00 (33.49%)
10mg
A288900-10mg
3 在庫あり
—

$271.90

$407.90
保存 $136.00 (33.34%)
25mg
A288900-25mg
3 在庫あり
—

$593.90

$890.90
保存 $297.00 (33.34%)
50mg
A288900-50mg
3 在庫あり
—

$1,069.90

$1,604.90
保存 $535.00 (33.34%)
100mg
A288900-100mg
2 在庫あり
—

$1,924.90

$2,887.90
保存 $963.00 (33.35%)
200mg
A288900-200mg
2 在庫あり
—

$3,463.90

$5,195.90
保存 $1,732.00 (33.33%)
500mg
A288900-500mg
2 在庫あり
—

$7,576.90

$11,365.90
保存 $3,789.00 (33.34%)
Enter a quantity for the sizes you want to add.
Bulk / Custom
♡ ウィッシュリスト ⇅ 比較リストに入れる ⎙ Print page
SDS
Safety data
COA
Certificate
DS
Datasheet
SP
Spec sheet
Specifications 名前と識別子 Documentation Advanced Data Taxonomic Classification 3 D構造 関連ターゲット（人間） 関連ターゲット（非人間） 作用メカニズム 証明書（CoA、COO、BSE/TSEと分析図） 化学的性質と物理的性質 ソリューション計算機 レビュー
🧪

Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

同義語
A 77-01 | A-77-01 | A77-01 | AKOS026750350 | DTXSID80440480 | E98766 | NCGC00379015-02 | BCP13726 | EX-A2200 | MS-24090 | C18H14N4 | SCHEMBL17559240 | 4-[3-(6-Methyl-pyridin-2-yl)-1H-pyrazol-4-yl]-quinoline | 4-[3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl]qu
仕様と純度
≥98%
生化学的・生理学的メカニズム
Potent TGF-βRI (ALK-5) inhibitor (IC50= 34 nM). Inhibits TGF-β transcriptional activation. Inhibits TGF-β-induced proliferation of lung epithelial cells and SMAD phosphorylation. Inhibits TGF-β-induced epithelial-to-mesenchymal transition (EMT). Also inh
保管条件
Store at -20°C
入荷
Ice chest + Ice pads
この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。
アクションタイプ
INHIBITOR
純度
≥98%
名前と識別子
パブケム・シド528762978
カノニカル・スマイルCC1=NC(=CC=C1)C2=C(C=NN2)C3=CC=NC4=CC=CC=C34
IUPAC Name4-[5-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl]quinoline
InChIKeyKJTYZDORHCDZPS-UHFFFAOYSA-N
INCHI1S/C18H14N4/c1-12-5-4-8-17(21-12)18-15(11-20-22-18)13-9-10-19-16-7-3-2-6-14(13)16/h2-11H,1H3,(H,20,22)
異性体SMILES CC1=NC(=CC=C1)C2=C(C=NN2)C3=CC=NC4=CC=CC=C34
分子量 286.33
Reaxy-Rn 32705446
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=32705446&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
分類Quinolines and derivatives
SubclassNot available
Intermediate Tree Nodes Not available
Direct ParentQuinolines and derivatives
Alternative Parents Methylpyridines  Benzenoids  Pyrazoles  Heteroaromatic compounds  Azacyclic compounds  Organonitrogen compounds  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Quinoline - Methylpyridine - Benzenoid - Pyridine - Heteroaromatic compound - Pyrazole - Azole - Azacycle - Organic nitrogen compound - Hydrocarbon derivative - Organonitrogen compound - Aromatic heteropolycyclic compound
説明This compound belongs to the class of organic compounds known as quinolines and derivatives. These are compounds containing a quinoline moiety, which consists of a benzene ring fused to a pyrimidine ring to form benzo[b]azabenzene.
External Descriptors Not available
3 D構造
インタラクティブ化学構造モデル





関連ターゲット（人間）
TGFBR1 Tchem TGF-beta receptor type-1 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MAPK14 Tchem MAP kinase p38 alpha (12866 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TGFBR1 Tchem TGF-beta receptor type I (3786 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
関連ターゲット（非人間）
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
作用メカニズム
証明書（CoA、COO、BSE/TSEと分析図）
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

7 results found

Lot NumberCertificate Type日付商品
C2321092Certificate of AnalysisJan 03, 2023 A288900
C2321093Certificate of AnalysisJan 03, 2023 A288900
C2321094Certificate of AnalysisJan 03, 2023 A288900
C2321095Certificate of AnalysisJan 03, 2023 A288900
C2321096Certificate of AnalysisJan 03, 2023 A288900
C2321155Certificate of AnalysisJan 03, 2023 A288900
C2321211Certificate of AnalysisJan 03, 2023 A288900
化学的性質と物理的性質
溶解度Solvent:DMSO, Max Conc. mg/mL: 28.63, Max Conc. mM: 100; Solvent:1eq. HCl, Max Conc. mg/mL: 14.32, Max Conc. mM: 50
分子量286.300 g/mol
XLogP33.100
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count2
Exact Mass286.122 Da
Monoisotopic Mass286.122 Da
Topological Polar Surface Area54.500 Ų
Heavy Atom Count22
Formal Charge0
Complexity374.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
ソリューション計算機
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