α-Thrombin , CAS No.9002-04-4

CAS: 9002-04-4 Cat. No.: np330890 分子式: C₁₂H₁₀ClN₃S 分子量: 263.75 EC番号: 232-648-7 PubChem CID: 65045

GRADE & PURITY Bioactive, ActiBioPure™, Native, High Performance, EnzymoPure™, from Human plasma; ≥2700 NIH U/mg protein; Pre-lyophilization Protein Concentration: See COA

Accession #

P00734

Bioactivity

≥2700 NIH U/mg protein

概要

The Human Thrombin was activated from homogeneous human prothrombin by activation with Factor Xa, Factor Va, and phospholipid. These activating enzymes were removed after activation. Complete activation was observed on SDS-PAGE. This activated enzyme has a minimum activity of 2,700 NIH units/mg when compared to NIH standard thrombin.

Extinction Coefficient (1%) = 18.3 

The above protein was purified from Human plasma units that test negative for antibodies to HBc, HCV, HIV 1/2, HTLV-I/II, and non reactive for HBsAg, HIV-1 RNA, HCV RNA, HBV DNA and Syphilis by FDA approved tests. Donors are screened for CJD.

Protein is for research use only; not for human use.

Specifications

Product Name

α-Thrombin , CAS No.9002-04-4

同義語

Human Alpha Thrombin | Human α-Thrombin | Human alpha-Thrombin Native Protein | Factor IIa, Human Plasma | Coagulation factor IIa | F2 | PT | THPH1 | RPRGL2

等級

ActiBioPure™, Bioactive, High Performance, Native, EnzymoPure™

仕様と純度

Bioactive, ActiBioPure™, Native, High Performance, EnzymoPure™, from Human plasma; ≥2700 NIH U/mg protein; Pre-lyophilization Protein Concentration: See COA

生化学的・生理学的メカニズム

Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing. Activates coagulation

生物活性

≥2700 NIH U/mg protein

アクセス番号

P00734

予想分子量

37 kDa

CAS

9002-04-4

酵素委員会番号

EC 3.4.21.5

分子タイプ

酵素

Product Line

biological_products

製品の性質

ナクレ

NA.54

保管と配送

集中

from Human plasma; ≥2700 NIH U/mg protein; Pre-lyophilization Protein Concentration: See COA

再構成

We suggest hydrating the protein with a good quality water to the original volume (See COA). After hydration aliquot into a useful (one time use) size and freeze at -80℃.

保管条件

Store at 2-8°C

入荷

Wet ice

安定性と保管

Store at 2-8℃ long term. Upon reconstitution, it is recommended to aliquot and freeze at -80℃.