ACY-957 - Moligand™, ≥98% , CAS No.1609389-52-7

CAS: 1609389-52-7 Cat. No.: A650992 分子式: C₂₄H₂₃N₅OS 分子量: 429.54

GRADE & PURITY Moligand™, ≥98%

Synonyms

HDAC Inhibitor C001 | N-(2-Amino-5-(thiophen-2-yl)phenyl)-2-(piperazin-1-yl)quinoline-6-carboxamide

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

概要

ACY-957 is an orally active and selective inhibitor of HDAC1 and HDAC2 , with IC 50 s of 7 nM, 18 nM, and 1300 nM against HDAC1/2/3, respectively, and shows no inhibition on HDAC4/5/6/7/8/9

In Vitro

ACY-957 is a selective inhibitor of HDAC1 and HDAC2, with IC 50 s of 7 nM, 18 nM, and 1300 nM against HDAC1/2/3, respectively, and shows no inhibition on HDAC4/5/6/7/8/9. ACY-957 has an IC 50 of 304 nM for HDAC2 in primary hematopoietic progenitors. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:HDAC1 7 nM (IC 50 ) HDAC2 18 nM (IC 50 ) HDAC3 1300 nM (IC 50 )

Specifications

同義語

HDAC Inhibitor C001 | N-(2-Amino-5-(thiophen-2-yl)phenyl)-2-(piperazin-1-yl)quinoline-6-carboxamide

仕様と純度

Moligand™, ≥98%

生化学的・生理学的メカニズム

ACY-957 is an selective inhibitor of HDAC1 and HDAC2, with IC50s of 7 nM, 18 nM, and 1300 nM against HDAC1/2/3, respectively, and shows no inhibition on HDAC4/5/6/7/8/9.

保管条件

Store at -20°C

入荷

Ice chest + Ice pads

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

等級

Moligand™

アクションタイプ

INHIBITOR

純度

≥98%

名前と識別子

• 分子量: 429.54

化学的性質と物理的性質

• 溶解度: DMSO : 83.33 mg/mL (194.00 mM; Need ultrasonic)