Adezmapimod hydrochloride - Moligand™, 10 mM in DMSO , CAS No.869185-85-3

CAS: 869185-85-3 Cat. No.: A1493543 分子式: C₂₁H₁₆FN₃OS.HCl 分子量: 413.9 EC番号: 112-725-0 PubChem CID: 16760644

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Desiccated,Store at -80°C

Shipped In

Dry ice packs + Cold packs

概要

Adezmapimod (SB 203580; RWJ 64809) hydrochloride is a selective and ATP-competitive p38 MAPK inhibitor with IC 50 s of 50 nM and 500 nM for SAPK2a/p38 and SAPK2b/p38β2 , respectively. Adezmapimod hydrochloride inhibits LCK , GSK3β and PKBα with IC 50 s of 100-500-fold higher than that for SAPK2a/p38. Adezmapimod hydrochloride does not disrupt JNK activity and is an autophagy and mitophagy activator.

Specifications

仕様と純度

Moligand™, 10 mM in DMSO

保管条件

Desiccated,Store at -80°C

入荷

Dry ice packs + Cold packs

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

等級

Moligand™

名前と識別子

• 異性体SMILES: CS(=O)C1=CC=C(C=C1)C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F.Cl
• PubChem CID: 16760644
• 分子量: 413.9