Name: Adomeglivant - Moligand™, ≥98% , Antagonist of glukagon receptor, CAS No.1488363-78-5, Antagonist of glukagon receptor
SKU: A412451
Availability: InStock

Adomeglivant - Moligand™, ≥98% , Antagonist of glukagon receptor, CAS No.1488363-78-5, Antagonist of glukagon receptor

CAS: 1488363-78-5 Cat. No.: A412451 分子式: C₃₂H₃₆F₃NO₄ 分子量: 555.63

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Adomeglivant - Moligand™, ≥98% CAS No(1488363-78-5) by Aladdin Scientific

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注文可能

GRADE & PURITY Moligand™ ? ≥98%

Synonyms

F85410 | AKOS040741049 | FASLTMSUPQDLIB-MHZLTWQESA-N | A858152 | ADOMEGLIVANT [WHO-DD] | .BETA.-ALANINE, N-(4-((1S)-1-((4'-(1,1-DIMETHYLETHYL)-2,6-DIMETHYL(1,1'-BIPHENYL)-4-YL)OXY)-4,4,4-TRIFLUOROBUTYL)BENZOYL)- | MS-30128 | UNII-74Z5ZL2KVG | 1488363-78-5

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

概要 Specifications 製品の性質名前と識別子 Documentation Advanced Data Taxonomic Classification 3 D構造関連ターゲット（人間）関連ターゲット（非人間）作用メカニズム証明書（CoA、COO、BSE/TSEと分析図）化学的性質と物理的性質ソリューション計算機レビュー

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Why this grade

Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

概要

Information

Adomeglivant Adomeglivant (LY2409021) is a potent and selective antagonist of glukagon receptor that is used as a chronic treatment for type 2 diabetes.

Adomeglivant (LY2409021) is a potent, selective glukagon receptor (GluR) allosteric antagonist. Adomeglivant is widely used in the research for type 2 diabetes mellitus.

Targets

Glukagon Receptor

Specifications

同義語

仕様と純度

Moligand™, ≥98%

生化学的・生理学的メカニズム

Adomeglivant (LY2409021) is a potent and selective antagonist of glukagon receptor that is used as a chronic treatment for type 2 diabetes.

保管条件

Store at -20°C

入荷

Ice chest + Ice pads

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

等級

Moligand™

アクションタイプ

ANTAGONIST

作用メカニズム

Antagonist of glukagon receptor

純度

≥98%

製品の性質

ALogP	7.839
hba_count	3
HBD数	1
回転可能な結合	12

名前と識別子

パブケム・シド	488202541
パブケム・シド・ウル	https://pubchem.ncbi.nlm.nih.gov/substance/488202541
カノニカル・スマイル	CC1=CC(=CC(=C1C2=CC=C(C=C2)C(C)(C)C)C)OC(CCC(F)(F)F)C3=CC=C(C=C3)C(=O)NCCC(=O)O
IUPAC Name	3-[[4-[(1S)-1-[4-(4-tert-butylphenyl)-3,5-dimethylphenoxy]-4,4,4-trifluorobutyl]benzoyl]amino]propanoic acid
InChIKey	FASLTMSUPQDLIB-MHZLTWQESA-N
INCHI	1S/C32H36F3NO4/c1-20-18-26(19-21(2)29(20)23-10-12-25(13-11-23)31(3,4)5)40-27(14-16-32(33,34)35)22-6-8-24(9-7-22)30(39)36-17-15-28(37)38/h6-13,18-19,27H,14-17H2,1-5H3,(H,36,39)(H,37,38)/t27-/m0/s1
異性体SMILES	CC1=CC(=CC(=C1C2=CC=C(C=C2)C(C)(C)C)C)O[C@@H](CCC(F)(F)F)C3=CC=C(C=C3)C(=O)NCCC(=O)O
代替CAS番号	872260-20-3,1488363-78-5
MeSH用語	(+)-adomeglivant;(+-)-adomeglivant;(-)-adomeglivant;3-(4-((1R)-1-((4'-tert-butyl-2,6-dimethylbiphenyl-4-yl)oxy)-4,4,4-trifluorobutyl)benzamido)propanoic acid;3-(4-((1S)-1-((4'-tert-butyl-2,6-dimethylbiphenyl-4-yl)oxy)-4,4,4-trifluorobutyl)benzamido)propan
分子量	555.63
Reaxy-Rn	12479521
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=12479521&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Benzenoids
  - 分類 Benzene and substituted derivatives
    - Subclass Biphenyls and derivatives

Kingdom	Organic compounds
Superclass	Benzenoids
分類	Benzene and substituted derivatives
Subclass	Biphenyls and derivatives
Intermediate Tree Nodes	Not available
Direct Parent	Biphenyls and derivatives
Alternative Parents	Beta amino acids and derivatives Benzamides Phenylpropanes m-Xylenes Benzoyl derivatives Phenol ethers Phenoxy compounds Alkyl aryl ethers Secondary carboxylic acid amides Monocarboxylic acids and derivatives Carboxylic acids Organic oxides Hydrocarbon derivatives Carbonyl compounds Organofluorides Organonitrogen compounds Alkyl fluorides
Molecular Framework	Aromatic homomonocyclic compounds
Substituents	Biphenyl - Beta amino acid or derivatives - Benzamide - Benzoic acid or derivatives - Phenylpropane - Phenoxy compound - M-xylene - Xylene - Benzoyl - Phenol ether - Alkyl aryl ether - Secondary carboxylic acid amide - Carboxamide group - Monocarboxylic acid or derivatives - Ether - Carboxylic acid - Carboxylic acid derivative - Organohalogen compound - Alkyl fluoride - Carbonyl group - Organooxygen compound - Organic nitrogen compound - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Alkyl halide - Organofluoride - Organonitrogen compound - Aromatic homomonocyclic compound
説明	This compound belongs to the class of organic compounds known as biphenyls and derivatives. These are organic compounds containing to benzene rings linked together by a C-C bond.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

3 D構造

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レビュー

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Lot Number	Certificate Type	日付	商品
C2321105	Certificate of Analysis	Feb 08, 2023	A412451
C2321111	Certificate of Analysis	Feb 08, 2023	A412451
C2321121	Certificate of Analysis	Feb 08, 2023	A412451
C2321191	Certificate of Analysis	Feb 08, 2023	A412451
C2321227	Certificate of Analysis	Feb 08, 2023	A412451
C2321228	Certificate of Analysis	Feb 08, 2023	A412451
C2321238	Certificate of Analysis	Feb 08, 2023	A412451
C2321297	Certificate of Analysis	Feb 08, 2023	A412451
C2321302	Certificate of Analysis	Feb 08, 2023	A412451
C2321351	Certificate of Analysis	Feb 08, 2023	A412451

溶解度	Solubility (25°C) In vitro DMSO: 100 mg/mL (179.97 mM); Ethanol: 100 mg/mL (179.97 mM); Water: Insoluble;
DMSO（mg / mL）最大溶解度	100
DMSO（mM）最大溶解度	179.975883231647
水（mg / mL）最大溶解度	＜1
分子量	555.600 g/mol
XLogP3	8.100
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	11
Exact Mass	555.26 Da
Monoisotopic Mass	555.26 Da
Topological Polar Surface Area	75.600 Å²
Heavy Atom Count	40
Formal Charge	0
Complexity	798.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1