adrixetinib - Moligand™ , Inhibitor of AXL receptor tyrosine kinase;Inhibitor of colony stimulating factor 1 receptor;Inhibitor of MER proto-oncogene; tyrosine kinase, CAS No.A607426, Inhibitor of AXL receptor tyrosine kinase;Inhibitor of colony stimulating factor 1 receptor;Inhibitor of MER proto-oncogene; tyrosine kinase

CAS: A607426 Cat. No.: A607426 PubChem CID: 156440741

GRADE & PURITY Moligand™

Synonyms

HY-152830 | Adrixetinib | GLXC-26812 | JIJ7I9XO8B | 1H-Pyrazole-3-carboxamide, N-[5-[(6,7-dimethoxy-4-quinolinyl)oxy]-2-pyridinyl]-1-propyl-4-(2,2,2-trifluoroethoxy)- | SCHEMBL23456979 | GTPL12375 | N-[5-(6,7-dimethoxyquinolin-4-yl)oxypyridin-2-yl]-1-prop

Storage

Room temperature

Specifications

同義語

HY-152830 | Adrixetinib | GLXC-26812 | JIJ7I9XO8B | 1H-Pyrazole-3-carboxamide, N-[5-[(6,7-dimethoxy-4-quinolinyl)oxy]-2-pyridinyl]-1-propyl-4-(2,2,2-trifluoroethoxy)- | SCHEMBL23456979 | GTPL12375 | N-[5-(6,7-dimethoxyquinolin-4-yl)oxypyridin-2-yl]-1-prop

仕様と純度

Moligand™

保管条件

Room temperature

等級

Moligand™

アクションタイプ

INHIBITOR

作用メカニズム

Inhibitor of AXL receptor tyrosine kinase;Inhibitor of colony stimulating factor 1 receptor;Inhibitor of MER proto-oncogene; tyrosine kinase

名前と識別子

• カノニカル・スマイル: COc1cc2c(ccnc2cc1OC)Oc1ccc(nc1)NC(=O)c1nn(cc1OCC(F)(F)F)CCC
• IUPAC Name: N-[5-(6,7-dimethoxyquinolin-4-yl)oxypyridin-2-yl]-1-propyl-4-(2,2,2-trifluoroethoxy)pyrazole-3-carboxamide
• InChIKey: BWUUJXXFCSYLFW-UHFFFAOYSA-N
• INCHI: 1S/C25H24F3N5O5/c1-4-9-33-13-21(37-14-25(26,27)28)23(32-33)24(34)31-22-6-5-15(12-30-22)38-18-7-8-29-17-11-20(36-3)19(35-2)10-16(17)18/h5-8,10-13H,4,9,14H2,1-3H3,(H,30,31,34)
• 異性体SMILES: CCCN1C=C(C(=N1)C(=O)NC2=NC=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OC)OC)OCC(F)(F)F
• PubChem CID: 156440741

関連ターゲット（人間）

CSF1R Tclin Macrophage colony-stimulating factor 1 receptor (0 Activities)

Discover Target: CSF1R

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MERTK Tchem Tyrosine-protein kinase Mer (0 Activities)

Discover Target: MERTK

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

AXL Tchem Tyrosine-protein kinase receptor UFO (0 Activities)

Discover Target: AXL

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)