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ADTL-EI1712 is a potent, orally active, and selective dual-target inhibitor of ERK1 and ERK5 , inhibition rates of ERK1/5 at 1 μM are 93.54% and 89.35%, respectively. ADTL-EI1712 can induce regulated cell death, a form of cell death that relies on the activation of genetically encoded machinery, to overcome compensatory mechanism in specific cancer cells in vitro and in vivo.
| CAS | 2414916-45-1 |
|---|---|
| 保管条件 | Store at -20°C |
| 入荷 | Ice chest + Ice pads |
| Product Description | ADTL-EI1712 is a potent, orally active, and selective dual-target inhibitor of ERK1 and ERK5 , inhibition rates of ERK1/5 at 1 μM are 93.54% and 89.35%, respectively. ADTL-EI1712 can induce regulated cell death, a form of cell death that relies on the activation of genetically encoded machinery, to overcome compensatory mechanism in specific cancer cells in vitro and in vivo. |