AFMK is a metabolite of the pineal hormone melatonin that exhibits antioxidant, immunomodulatory and anti-inflammatory properties. AFMK was first detected in rat brain and was found to be useful as an index for melatonin synthesis and metabolism.

Application：

AFMK, antioxidant metabolite of Melatonin, attenuates X-ray-induced oxidative damage to DNA, proteins and lipids in mice. AFMK is a poorer scavenger. The pKa of AFMK at physiological pH is 8.7. Antioxidant capacity. AFMK improves the anti-tumor effect of Gemcitabine in PANC-1 cells through the modulation of apoptotic pathway.

仕様

同義語

仕様と純度

Moligand™, ≥98%

保管条件

Store at -20°C

入荷

Ice chest + Ice pads

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

等級

Moligand™

純度

≥98%

製品の性質

pKa

pKa: 13.79 (Predicted)

名前と識別子

パブケム・シド

528763037

カノニカル・スマイル

CC(=O)NCCC(=O)C1=C(C=CC(=C1)OC)NC=O

IUPAC Name

N-[3-(2-formamido-5-methoxyphenyl)-3-oxopropyl]acetamide

InChIKey

JYWNYMJKURVPFH-UHFFFAOYSA-N

INCHI

1S/C13H16N2O4/c1-9(17)14-6-5-13(18)11-7-10(19-2)3-4-12(11)15-8-16/h3-4,7-8H,5-6H2,1-2H3,(H,14,17)(H,15,16)

異性体SMILES

CC(=O)NCCC(=O)C1=C(C=CC(=C1)OC)NC=O

WGKドイツ

分子量

264.28

Reaxy-Rn

2866214

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2866214&ln=

ドキュメント

📋 安全データシート（SDS）

危険性、取扱い、保管、および規制遵守を網羅した包括的な文書。

<<<<<<< HEAD SDS をダウンロード → ======= SDS をダウンロード → >>>>>>> release248-p3

✅ 分析証明書（COA）

ロット固有の品質データ。ロット番号を入力して、正確な COA を取得してください。

COA を検索 →

📊 データシート

製品仕様と用途のクイックリファレンス概要。

データシートを見る →

🔬 仕様書

このグレードの完全な品質特性と合格基準。

仕様書を見る →

詳細データ

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organic oxygen compounds
  - 分類 Organooxygen compounds
    - Subclass Carbonyl compounds
      - Level5 Ketones
        Level6 Aryl ketones
        Level7 Phenylketones
        Level8 Alkyl-phenylketones

Kingdom	Organic compounds
Superclass	Organic oxygen compounds
分類	Organooxygen compounds
Subclass	Carbonyl compounds
Intermediate Tree Nodes	Ketones - Aryl ketones - Phenylketones
Direct Parent	Alkyl-phenylketones
Alternative Parents	Methoxyanilines Anilides Phenoxy compounds N-arylamides Methoxybenzenes Benzoyl derivatives Aryl alkyl ketones Anisoles Alkyl aryl ethers Vinylogous amides Acetamides Secondary carboxylic acid amides Organopnictogen compounds Organic oxides Hydrocarbon derivatives
Molecular Framework	Aromatic homomonocyclic compounds
Substituents	Alkyl-phenylketone - Methoxyaniline - Anilide - Phenoxy compound - Anisole - Benzoyl - Phenol ether - Methoxybenzene - N-arylamide - Aryl alkyl ketone - Alkyl aryl ether - Monocyclic benzene moiety - Benzenoid - Acetamide - Vinylogous amide - Secondary carboxylic acid amide - Carboxamide group - Ether - Carboxylic acid derivative - Hydrocarbon derivative - Organonitrogen compound - Organic oxide - Organic nitrogen compound - Organopnictogen compound - Aromatic homomonocyclic compound
説明	This compound belongs to the class of organic compounds known as alkyl-phenylketones. These are aromatic compounds containing a ketone substituted by one alkyl group, and a phenyl group.
External Descriptors	a small molecule
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

3 D構造

関連ターゲット（人間）

MTNR1A Tclin Melatonin receptor 1A (2519 Activities)

Discover Target: MTNR1A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

A498 (42825 Activities)

Lot Number	Certificate Type	日付	商品
B2506170	Certificate of Analysis	Jan 16, 2025	A336148
B2506171	Certificate of Analysis	Jan 16, 2025	A336148
B2506172	Certificate of Analysis	Jan 16, 2025	A336148
B2506173	Certificate of Analysis	Jan 16, 2025	A336148
B2506174	Certificate of Analysis	Jan 16, 2025	A336148
B2506175	Certificate of Analysis	Jan 16, 2025	A336148
B2506228	Certificate of Analysis	Jan 16, 2025	A336148
B2506230	Certificate of Analysis	Jan 16, 2025	A336148
B2506233	Certificate of Analysis	Jan 16, 2025	A336148
B2506234	Certificate of Analysis	Jan 16, 2025	A336148
B2506235	Certificate of Analysis	Jan 16, 2025	A336148
B2506237	Certificate of Analysis	Jan 16, 2025	A336148

溶解度	Soluble in ethanol (~5 mg/ml), DMSO (~30 mg/ml), DMF (~30 mg/ml), methanol, and water (1 mg/ml at 25° C).
屈折率	n20D1.56 (Predicted)
沸点（°C）	~589.4° C at 760 mmHg (Predicted)
融点（°C）	123-126° C
分子量	264.280 g/mol
XLogP3	0.600
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	6
Exact Mass	264.111 Da
Monoisotopic Mass	264.111 Da
Topological Polar Surface Area	84.500 Å²
Heavy Atom Count	19
Formal Charge	0
Complexity	333.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

AFMK - Moligand™, ≥98% , CAS No.52450-38-1

保管・配送

品質書類

文献的裏付け

概要

仕様

ドキュメント

📋 安全データシート（SDS）

✅ 分析証明書（COA）

📊 データシート

🔬 仕様書

詳細データ

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

顧客レビュー

グレードの選択でお困りですか？

View related series

関連商品