AGI-14100 is a metabolically stable and orally available mIDH1 inhibitor ( IC 50 =6 nM). The pharmacochemical optimization of AGI-14100 is aimed at eliminating hPXR activation, resulting in the final drug candidate AG-120. AG-120 can be used in the study of cancers carrying IDH1 mutations. The discovery and development of AGI-14100 can be used for further studies of mutant isocitrate dehydrogenase 1 ( mIDH1 ) inhibitors.
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How should this product be stored?
Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.
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This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 1448346-43-7, the molecular formula is C29H22ClF4N5O3, and the molecular weight is 599.96 g/mol.
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