AH3960 - Moligand™,≥99% , CAS No.862907-48-0

CAS: 862907-48-0 Cat. No.: A650765 分子式: C₁₃H₂₂N₄O₃ 分子量: 282.34 PubChem CID: 135508376

GRADE & PURITY Moligand™, ≥99%

Synonyms

AH-3960

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

概要

AH3960 is a selective parathyroid hormone 1 receptor (PTHR1) agonist and also an antagonist of wild-type/T877A mutant androgen receptor (AR). AH3960 exhibits pIC50 value against wild-type PTHR1 of 4.03, the IC50 against wild-type AR of 1.5 μM, and the IC50 against T877A mutant AR of 0.35 μM. AH3960 activates the cAMP and calcium signaling pathways. AH3960 inhibits adipocyte differentiation and the expression of adipocyte markers, and promotes early differentiation of osteoblasts. AH3960 is applicable to research related to osteoporosis and prostate cancer.

Specifications

同義語

AH-3960

仕様と純度

Moligand™,≥99%

保管条件

Store at -20°C

入荷

Ice chest + Ice pads

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

等級

Moligand™

アクションタイプ

AGONIST

純度

≥99%

名前と識別子

• カノニカル・スマイル: CCCCN1C(=C(C(=O)N(C1=O)CCCC)C(=N)N)O
• IUPAC Name: 1,3-dibutyl-4-hydroxy-2,6-dioxopyrimidine-5-carboximidamide
• InChIKey: VOYADQIFGGIKAT-UHFFFAOYSA-N
• INCHI: 1S/C13H22N4O3/c1-3-5-7-16-11(18)9(10(14)15)12(19)17(13(16)20)8-6-4-2/h18H,3-8H2,1-2H3,(H3,14,15)
• 異性体SMILES: CCCCN1C(=C(C(=O)N(C1=O)CCCC)C(=N)N)O
• PubChem CID: 135508376
• MeSH用語: 1,3-dibutyl-5-(diaminomethylene)pyrimidine-2,4,6-trione;AH-3960;AH3960;dibutyl-diaminomethylene-pyrimidine-2,4,6-trione
• 分子量: 282.34

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • 分類 Diazines
      • Subclass Pyrimidines and pyrimidine derivatives

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• 分類: Diazines
• Subclass: Pyrimidines and pyrimidine derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Hydroxypyrimidines
• Alternative Parents: Pyrimidones Hydropyrimidines Vinylogous amides Vinylogous acids Heteroaromatic compounds Ureas Lactams Carboximidamides Carboxamidines Azacyclic compounds Organopnictogen compounds Organooxygen compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Hydroxypyrimidine - Pyrimidone - Hydropyrimidine - Heteroaromatic compound - Vinylogous amide - Vinylogous acid - Urea - Lactam - Azacycle - Carboximidamide - Carboxylic acid amidine - Amidine - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Aromatic heteromonocyclic compound
• 説明: This compound belongs to the class of organic compounds known as hydroxypyrimidines. These are organic compounds containing a hydroxyl group attached to a pyrimidine ring. Pyrimidine is a 6-membered ring consisting of four carbon atoms and two nitrogen centers at the 1- and 3- ring positions.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

化学的性質と物理的性質

• 分子量: 282.340 g/mol
• XLogP3: 1.500
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 7
• Exact Mass: 282.169 Da
• Monoisotopic Mass: 282.169 Da
• Topological Polar Surface Area: 111.000 Ų
• Heavy Atom Count: 20
• Formal Charge: 0
• Complexity: 445.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

よくある質問

What is the purity of this product?

This product is supplied at ≥99% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 862907-48-0, the molecular formula is C13H22N4O3, and the molecular weight is 282.34 g/mol. InChIKey VOYADQIFGGIKAT-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.