Ailanthone - Moligand™, 10 mM in DMSO , CAS No.981-15-7

CAS: 981-15-7 Cat. No.: A1499879 分子式: C₂₀H₂₄O₇ 分子量: 376.40 EC番号: 683-145-8

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

概要

Ailanthone (Δ13-Dehydrochaparrinone) is a potent inhibitor of both full-length androgen receptor (AR) ( IC 50 =69 nM) and constitutively active truncated AR splice variants (AR 1-651 IC 50 =309 nM).

Specifications

仕様と純度

Moligand™, 10 mM in DMSO

保管条件

Store at -80°C

入荷

Dry ice packs + Cold packs

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

等級

Moligand™

アクションタイプ

INHIBITOR

名前と識別子

• 異性体SMILES: CC1=CC(=O)[C@H]([C@]2([C@H]1C[C@@H]3[C@]45[C@@H]2[C@]([C@@H](C(=C)[C@@H]4CC(=O)O3)O)(OC5)O)C)O
• RTECS: KT0930000
• 分子量: 376.40
• Reaxy-Rn: 1441126
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1441126&ln=

参考文献

1. Yue Zhang, Taiding Wu, Chang Li, Nianfang Luo, Jun Wang, Jingxian Li, Min Tian, Lei Liu, Ruiting Li, Jingyi Zhang.  (2025)  Ailanthone induces apoptosis in U-2OS cells through the endoplasmic reticulum stress.  Frontiers in Immunology,      [PMID:41112300] [10.3389/fimmu.2025.1633643]