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Aladdin™ Coupling Catalyst
注文可能
Storage
Store at 2-8°C
Shipped In
Wet ice
このグレードを選ぶ理由
ベースライン干渉を最小限に抑える必要がある、感度の高いクロマトグラフィーおよび分析ワークフロー向け。
保管・配送
Store at 2-8°C Wet ice に出荷。正確な仕様については、ロット固有の COA をご確認ください。
品質書類
SDS、COA、データシート、仕様書をダウンロードできます。ロット固有の COA はロット番号検索で入手可能です。
文献的裏付け
クロマトグラフィー、有機合成、クロスカップリング反応に関する 0 件の査読済み論文で引用されています。
概要
Product introduction：
Coupling Catalyst decreases reaction times and increases aldehyde-hydrazide coupling efficiency, resulting in greater than 90% coupling of glycoproteins in 4 hours.
Features of the GlycoLink Coupling Catalyst:
• Optimized—catalyzes aldehyde-hydrazide and aldehyde-alkoxyamine conjugation reaction
• Efficient—maximizes coupling efficiency and decreases required coupling reaction incubation time
• Gentle—does not interfere with protein function and is easily removed by desalting or dialysis
The GlycoLink Coupling Catalyst is a two component kit composed of aniline and sodium acetate buffer. The catalyst accelerates the coupling rate of hydrazide and alkoxyamine moieties with reactive aldehydes that have been generated by periodate-oxidation of cis-diols in glycoproteins. The GlycoLink Coupling Catalyst increases the coupling efficiency of these reactions, decreasing the molar excess amounts of labeling reagents that are required for conjugation reactions. The catalyst is also useful for increasing the binding efficiency of oxidized glycoproteins or other carbohydrate-containing molecules to hydrazide resins.
Applications
• Labeling aldehyde-containing molecules with alkoxyamine-biotins
• Labeling aldehyde-containing molecules with hydrazide-biotins
• Increase coupling efficiency of aldehyde-containing molecules to hydrazide resin
Producing reactive aldehydes via sodium meta-periodate oxidation of cis-diols in glycoproteins is a useful technique for variety of protein labeling and detection methods. The GlycoLink Coupling Catalyst (aniline) increases the efficiency of these reactions by acting as a nucleophilic catalyst that accelerates bond formation through a Schiff base intermediate. The catalyst also reduces the amount (molar excess) of hydrazide or alkoxyamine required in labeling reactions, thereby eliminating the need for DMSO to solubilize high concentrations of labeling reagent.
More Product Data
•Improved immobilization and conjugation of glycoproteins
Features of the GlycoLink Coupling Catalyst:
• Optimized—catalyzes aldehyde-hydrazide and aldehyde-alkoxyamine conjugation reaction
• Efficient—maximizes coupling efficiency and decreases required coupling reaction incubation time
• Gentle—does not interfere with protein function and is easily removed by desalting or dialysis
The GlycoLink Coupling Catalyst is a two component kit composed of aniline and sodium acetate buffer. The catalyst accelerates the coupling rate of hydrazide and alkoxyamine moieties with reactive aldehydes that have been generated by periodate-oxidation of cis-diols in glycoproteins. The GlycoLink Coupling Catalyst increases the coupling efficiency of these reactions, decreasing the molar excess amounts of labeling reagents that are required for conjugation reactions. The catalyst is also useful for increasing the binding efficiency of oxidized glycoproteins or other carbohydrate-containing molecules to hydrazide resins.
Applications
• Labeling aldehyde-containing molecules with alkoxyamine-biotins
• Labeling aldehyde-containing molecules with hydrazide-biotins
• Increase coupling efficiency of aldehyde-containing molecules to hydrazide resin
Producing reactive aldehydes via sodium meta-periodate oxidation of cis-diols in glycoproteins is a useful technique for variety of protein labeling and detection methods. The GlycoLink Coupling Catalyst (aniline) increases the efficiency of these reactions by acting as a nucleophilic catalyst that accelerates bond formation through a Schiff base intermediate. The catalyst also reduces the amount (molar excess) of hydrazide or alkoxyamine required in labeling reactions, thereby eliminating the need for DMSO to solubilize high concentrations of labeling reagent.
More Product Data
•Improved immobilization and conjugation of glycoproteins
• Form:Liquid
仕様
保管条件
Store at 2-8°C
入荷
Wet ice
この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。
ドキュメント
📋 安全データシート（SDS）
危険性、取扱い、保管、および規制遵守を網羅した包括的な文書。
<<<<<<< HEAD SDS をダウンロード → ======= SDS をダウンロード → >>>>>>> release248-p3詳細データ
証明書（CoA、COO、BSE/TSEと分析図）
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
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レビュー
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