AM 1172 - ≥98%(HPLC) , CAS No.251908-92-6

CAS: 251908-92-6 Cat. No.: A287204 分子式: C₂₇H₃₉NO₂ 分子量: 409.6 PubChem CID: 10364179

GRADE & PURITY ≥98%(HPLC)

Synonyms

SCHEMBL14105462 | N-arachidonyl 4-hydroxybenzamide | UNII-G5DZB59PZA | AM1172 | AM-1172 | AM2201-d5 | BA168613 | SR-01000946702 | SR-01000946702-1 | AKOS024457594 | 4-hydroxy-N-[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenyl]benzamide | Benzamide, N-(5Z,8Z,11Z

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

概要

AM1172 is metabolically stable anandamide uptake inhibitor and FAAH inhibitor.

Specifications

同義語

SCHEMBL14105462 | N-arachidonyl 4-hydroxybenzamide | UNII-G5DZB59PZA | AM1172 | AM-1172 | AM2201-d5 | BA168613 | SR-01000946702 | SR-01000946702-1 | AKOS024457594 | 4-hydroxy-N-[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenyl]benzamide | Benzamide, N-(5Z,8Z,11Z

仕様と純度

≥98%(HPLC)

生化学的・生理学的メカニズム

Metabolically stable anandamide uptake inhibitor (IC50= 2.1 - 2.5μM) and fatty acid amide hydrolase (FAAH) inhibitor (Ki= 3.18μM). InhibitsN-arachidonylethanolamine (AEA) accumulation (IC50= 24μM) and hydrolysis (Ki= 3μM), and inhibitsN-palmitoylethanolam

保管条件

Store at -20°C

入荷

Ice chest + Ice pads

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

アクションタイプ

INHIBITOR

純度

≥98%(HPLC)

名前と識別子

カノニカル・スマイル

CCCCCC=CCC=CCC=CCC=CCCCCNC(=O)C1=CC=C(C=C1)O

IUPAC Name

4-hydroxy-N-[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenyl]benzamide

InChIKey

XCWBOAHOJHPWLA-DOFZRALJSA-N

INCHI

1S/C27H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-24-28-27(30)25-20-22-26(29)23-21-25/h6-7,9-10,12-13,15-16,20-23,29H,2-5,8,11,14,17-19,24H2,1H3,(H,28,30)/b7-6-,10-9-,13-12-,16-15-

異性体SMILES

CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCCNC(=O)C1=CC=C(C=C1)O

PubChem CID

10364179

分子量

409.6

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • 分類 Benzene and substituted derivatives
      • Subclass Benzoic acids and derivatives

• Kingdom: Organic compounds
• Superclass: Benzenoids
• 分類: Benzene and substituted derivatives
• Subclass: Benzoic acids and derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Benzamides
• Alternative Parents: Benzoyl derivatives 1-hydroxy-2-unsubstituted benzenoids Secondary carboxylic acid amides Organooxygen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Benzamide - Benzoyl - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Secondary carboxylic acid amide - Carboxamide group - Carboxylic acid derivative - Organic nitrogen compound - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Aromatic homomonocyclic compound
• 説明: This compound belongs to the class of organic compounds known as benzamides. These are organic compounds containing a carboxamido substituent attached to a benzene ring.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

化学的性質と物理的性質

• 溶解度: Soluble in ethanol (supplied pre-dissolved in anhydrous ethanol, 10(mg/mL))
• 分子量: 409.600 g/mol
• XLogP3: 7.800
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 16
• Exact Mass: 409.298 Da
• Monoisotopic Mass: 409.298 Da
• Topological Polar Surface Area: 49.300 Ų
• Heavy Atom Count: 30
• Formal Charge: 0
• Complexity: 525.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 4
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 4
• Covalently-Bonded Unit Count: 1