Amiloride - Moligand™, 10 mM in DMSO , CAS No.2609-46-3

CAS: 2609-46-3 Cat. No.: A1499343 分子式: C₆H₈ClN₇O 分子量: 229.63 Beilstein Registry Number: 616612 EC番号: 220-024-7

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

概要

Amiloride (MK-870) is an inhibitor of both epithelial sodium channel ( ENaC) and urokinase-type plasminogen activator receptor ( uTPA). Amiloride is a blocker of polycystin-2 (PC2; TRPP2) channel.

Specifications

仕様と純度

Moligand™, 10 mM in DMSO

保管条件

Store at -80°C

入荷

Dry ice packs + Cold packs

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

等級

Moligand™

製品の性質

• pKa: pKa: 7.81 (Predicted), pKa: 3.78 (Predicted)
• 氣のデータ: uPA: Ki= 2.51 μM (human); Adenosine A2A-R: Ki= 3.28 μM (human); Solute carrier family 22 member 2: Ki= 4.7 μM (rat); Solute carrier family 22 member 1: Ki= 6.9 μM (rat); Amine oxidase, copper containing: Ki= 10 μM (rat)

名前と識別子

• 異性体SMILES: C1(=C(N=C(C(=N1)Cl)N)N)C(=O)N=C(N)N
• 代替CAS番号: 2016-88-8;17440-83-4
• 分子量: 229.63
• Beilstein: 616612

化学的性質と物理的性質

• 屈折率: n20D1.89 (Predicted)
• 沸点（°C）: ~557.9° C at 760 mmHg (Predicted)
• 融点（°C）: 185.21° C (Predicted)

参考文献

1. Ruoning Wang, Qifan Liang, Xinru Zhang, Zhenning Di, Xiaohong Wang, Liuqing Di.  (2022)  Tumor-derived exosomes reversing TMZ resistance by synergistic drug delivery for glioma-targeting treatment.  COLLOIDS AND SURFACES B-BIOINTERFACES,      [PMID:35487070] [10.1016/j.colsurfb.2022.112505]

よくある質問

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 2609-46-3, the molecular formula is C6H8ClN7O, and the molecular weight is 229.63 g/mol.