Amitriptyline-d6 Hydrochloride - ≥99 atom% D,≥98% , CAS No.203645-63-0

CAS: 203645-63-0 Cat. No.: A357463 分子式: C₂₀H₁₈D₆ClN 分子量: 319.90 EC番号: 846-446-7

GRADE & PURITY ≥99 atom% D,≥98%

Synonyms

3-(5,6-dihydrodibenzo[1,2-a:2',1'-d][7]annulen-11-ylidene)-N,N-bis(trideuteriomethyl)propan-1-amine;hydrochloride | 3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine-d6 Hydrochloride

Storage

Store at 2-8°C,Protected from light

Shipped In

Wet ice

概要

Amitriptyline-d6 (hydrochloride) is the deuterium labeled Amitriptyline hydrochloride. Amitriptyline hydrochloride is an inhibitor of serotonin reuptake transporter (SERT) and noradrenaline reuptake transporter (NET), with Kis of 3.45 nM and 13.3 nM for human SERT and NET, respectively. Amitriptyline hydrochloride also weakly binds to dopamine reuptake transporter (DAT) with a Ki of 2.58 μM. Amitriptyline hydrochloride also inhibits adrenergic, muscarinic, histamine and 5-HT receptors. Amitriptyline hydrochloride is a TrkA and TrkB receptors agonist with potent neurotrophic activity. Amitriptyline hydrochloride has antidepressant activity

Specifications

同義語

3-(5,6-dihydrodibenzo[1,2-a:2',1'-d][7]annulen-11-ylidene)-N,N-bis(trideuteriomethyl)propan-1-amine;hydrochloride | 3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine-d6 Hydrochloride

仕様と純度

≥99 atom% D,≥98%

保管条件

Store at 2-8°C,Protected from light

入荷

Wet ice

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

純度

≥99 atom% D,≥98%

名前と識別子

パブケム・シド

528773940

カノニカル・スマイル

CN(C)CCC=C1C2=CC=CC=C2CCC3=CC=CC=C31.Cl

IUPAC Name

3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)-N,N-bis(trideuteriomethyl)propan-1-amine;hydrochloride

InChIKey

KFYRPLNVJVHZGT-TXHXQZCNSA-N

INCHI

1S/C20H23N.ClH/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20;/h3-6,8-12H,7,13-15H2,1-2H3;1H/i1D3,2D3;

異性体SMILES

[2H]C([2H])([2H])N(CCC=C1C2=CC=CC=C2CCC3=CC=CC=C31)C([2H])([2H])[2H].Cl

代替CAS番号

549-18-8（Unlabelled ）

UN番号

2811

包装グループ

III

分子量

319.90

Reaxy-Rn

4164595

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4164595&ln=

化学的性質と物理的性質

• 感度: Light sensitive；Moisture sensitive
• 融点（°C）: 192-195° C