Determine the necessary mass, volume, or concentration for preparing a solution.
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Amitriptyline inhibits serotonin receptor, norepinephrine receptor, 5-HT4, 5-HT2 and sigma 1 receptor with IC50 of 3.45 nM, 13.3 nM, 7.31 nM, 235 nM and 287 nM, respectively.
Amitriptyline hydrochloride is a tricyclic antidepressant drug. Amitriptyline hydrochloride inhibits the norepinephrine and serotonin transporters but has a high affinity for α1-adrenergic, serotonin and muscarinic acetylcholine receptors.
Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| 分類 | Dibenzocycloheptenes |
| Subclass | Not available |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Dibenzocycloheptenes |
| Alternative Parents | Trialkylamines Organopnictogen compounds Hydrochlorides Hydrocarbon derivatives |
| Molecular Framework | Aromatic homopolycyclic compounds |
| Substituents | Dibenzocycloheptene - Tertiary aliphatic amine - Tertiary amine - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Hydrochloride - Organonitrogen compound - Amine - Aromatic homopolycyclic compound |
| 説明 | This compound belongs to the class of organic compounds known as dibenzocycloheptenes. These are compounds containing a dibenzocycloheptene moiety, which consists of two benzene rings connected by a cycloheptene ring. |
| External Descriptors | Not available |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | 日付 | 商品 |
|---|---|---|---|
| Certificate of Analysis | Sep 01, 2026 | A129730 | |
| Certificate of Analysis | Sep 01, 2026 | A129730 | |
| Certificate of Analysis | Sep 01, 2026 | A129730 | |
| Certificate of Analysis | May 09, 2026 | A129730 | |
| Certificate of Analysis | May 09, 2026 | A129730 | |
| Certificate of Analysis | May 09, 2026 | A129730 | |
| Certificate of Analysis | May 09, 2026 | A129730 | |
| Certificate of Analysis | Mar 18, 2026 | A129730 | |
| Certificate of Analysis | Feb 04, 2026 | A129730 | |
| Certificate of Analysis | Feb 04, 2026 | A129730 | |
| Certificate of Analysis | Mar 21, 2025 | A129730 | |
| Certificate of Analysis | Mar 21, 2025 | A129730 | |
| Certificate of Analysis | Mar 21, 2025 | A129730 | |
| Certificate of Analysis | Mar 21, 2025 | A129730 | |
| Certificate of Analysis | Mar 21, 2025 | A129730 | |
| Certificate of Analysis | Mar 21, 2025 | A129730 | |
| Certificate of Analysis | May 07, 2024 | A129730 | |
| Certificate of Analysis | May 07, 2024 | A129730 |
| 溶解度 | Soluble in Chloroform |
|---|---|
| 感度 | Light sensitive;Moisture sensitive |
| 融点(°C) | 195 °C |
| 分子量 | 313.900 g/mol |
| XLogP3 | |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 3 |
| Exact Mass | 313.16 Da |
| Monoisotopic Mass | 313.16 Da |
| Topological Polar Surface Area | 3.200 Ų |
| Heavy Atom Count | 22 |
| Formal Charge | 0 |
| Complexity | 331.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 2 |