AN-3485 is a benzoxaborole analog, Toll-Like Receptor(TLR) inhibitor with IC 50 values ranging from 18 to 580 nM.
IC50& Target:IC50：AN-3485 inhibits TLR2-, TLR3-, TLR4-, and TLR5-mediates TNF-a, IL-1b, and IL-6 release with IC 50 values of human PBMCs (103±68 nM, 68±63 nM, 72±33 nM)and isolated monocytes (77±26 nM,18±6.7 nM,32±6.5 nM)
その他の情報
| CAS | 1213827-99-6 |
|---|---|
| 集中 | 10mM in DMSO |
| 仕様と純度 | 10mM in DMSO |
| 保管条件 | Store at -80°C |
| 入荷 | Dry ice packs + Cold packs |
| Product Description | AN-3485 is a benzoxaborole analog, Toll-Like Receptor(TLR) inhibitor with IC 50 values ranging from 18 to 580 nM. IC50& Target:IC50：AN-3485 inhibits TLR2-, TLR3-, TLR4-, and TLR5-mediates TNF-a, IL-1b, and IL-6 release with IC 50 values of human PBMCs (103±68 nM, 68±63 nM, 72±33 nM)and isolated monocytes (77±26 nM,18±6.7 nM,32±6.5 nM) |
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