Anticancer agent 157 (compound 15) is a NO inhibitor ( IC 50 =0.62 μg/mL) with anti-inflammatory and anticancer activities. Anticancer agent 157 can bind to iNOS (inducible NO synthase ) and caspase 8 , causing nuclear fragmentation and chromatin condensation, inducing apoptosis. Anticancer agent 157 inhibits HT29 colon cancer cells ( IC 50 =2.45 μg/mL), Hep-G2 liver cancer cells ( IC 50 =3.25 μg/mL), and B16-F10 murine melanoma cells ( IC 50 =3.84 μg/mL).
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How should this product be stored?
Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.
How is this product shipped?
This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is A1419035, the molecular formula is C14H20O2, and the molecular weight is 220.31 g/mol.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.
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