Antitumor agent-182 (Compound 12a) decreases mitochondrial membrane potential ( MMP ) and enhances ROS levels. Antitumor agent-182 arrests the cell cycle at G0/G1 phase, induces apoptosis in HeLa. Antitumor agent-182 inhibits the proliferation of HeLa, PC-3 and HCT-15 with IC 50 s of 8.83, 10.07 and 7.84 μM, respectively.
その他の情報
| CAS | A1417185 |
|---|---|
| 保管条件 | Store at -20°C |
| 入荷 | Ice chest + Ice pads |
| Product Description | Antitumor agent-182 (Compound 12a) decreases mitochondrial membrane potential ( MMP ) and enhances ROS levels. Antitumor agent-182 arrests the cell cycle at G0/G1 phase, induces apoptosis in HeLa. Antitumor agent-182 inhibits the proliferation of HeLa, PC-3 and HCT-15 with IC 50 s of 8.83, 10.07 and 7.84 μM, respectively. |
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