AP C5 - ≥98%(HPLC) , CAS No.2234272-10-5

CAS: 2234272-10-5 Cat. No.: A288897 分子式: C₁₆H₁₃N₅ 分子量: 275.31

グレード＆純度 ≥98%(HPLC)

Synonyms

4-[4-(1H-Imidazol-1-yl)phenyl]-N-2-propyn-1-yl-2-pyrimidinamine

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

概要

Explanation：

AP C5 is a potent and selective protein kinase G type II (PKG2) inhibitor (pIC50 = 7.2). Displays >20-fold selectivity for PKG2 over PKG1 and PKA (pIC50 values are 4.6 and 4.8 for PKG1 and PKA, respectively). Blocks 8-pCPT-cGMP-dependent VASP phosphorylation in intestinal organoids. Also attenuates toxin-stimulated anion secretory responses in mouse intestinal tissue.

仕様

同義語

4-[4-(1H-Imidazol-1-yl)phenyl]-N-2-propyn-1-yl-2-pyrimidinamine

仕様と純度

≥98%(HPLC)

保管条件

Store at -20°C

入荷

Ice chest + Ice pads

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

純度

≥98%(HPLC)

名前と識別子

カノニカル・スマイル

C#CCNC1=NC=CC(=N1)C2=CC=C(C=C2)N3C=CN=C3

IUPAC Name

4-(4-imidazol-1-ylphenyl)-N-prop-2-ynylpyrimidin-2-amine

InChIKey

QKHQFSQJQKGFAA-UHFFFAOYSA-N

INCHI

1S/C16H13N5/c1-2-8-18-16-19-9-7-15(20-16)13-3-5-14(6-4-13)21-11-10-17-12-21/h1,3-7,9-12H,8H2,(H,18,19,20)

分子量

275.31

Reaxy-Rn

32869944

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=32869944&ln=

化学的性質と物理的性質

• 溶解度: Solvent:DMSO, Max Conc. mg/mL: 27.53, Max Conc. mM: 100; Solvent:1eq. HCl, Max Conc. mg/mL: 27.53, Max Conc. mM: 100