GRADE & PURITYBioactive?Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure.Native?Native grade — protein/biomolecule in its natural (non-recombinant, non-denatured) form. Use when native structure and activity are required.≥95%(SDS-PAGE)See COA
Bioactive, Native, ≥95%(SDS-PAGE), See COA Bioactive,Native for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -80°C,Avoid repeated freezing and thawing Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
概要
Apolipoprotein E serves as a ligand for low density receptors and participates in the transport and redistribution of cholesterol and other lipids. Other functions include immunoregulation and cell growth modulation and differentiation. Apo E is thought to be involved in tissue repair as increased amounts of the protein are found at sites of peripheral nerve injury and regeneration. A mutant form is associated with familial type III hyperlipoproteinemia. The concentration of Apo E in normal plasma is 5 mg per 100 ml.
Researchers' source for Alzheimer's Disease Research.
Extinction Coefficient: 1.31
Prepared from fresh, non-frozen plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
Aladdin products are laboratory reagents and are not to be administered to humans or used for any drug purpose. For research use only.
Specifications
Product Name
Apolipoprotein E from Human Plasma
同義語
Apolipoprotein E, Human Plasma | APOE | AD2 | LPG | APO-E | ApoE4 | LDLCQ5
等級
Bioactive, Native
仕様と純度
Bioactive, Native, ≥95%(SDS-PAGE), See COA
生化学的・生理学的メカニズム
Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues.
Post-translational: Synthesized with the
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Products are supplied to verified businesses, institutions, and qualified professionals for research and development use only. Not for use in humans, animals, diagnosis, or therapy.
