AT 1001 - ≥99% , CAS No.1314801-63-2

CAS: 1314801-63-2 Cat. No.: A1438246 PubChem CID: 53302872

GRADE & PURITY ≥99%

Storage

Store at 2-8°C

Shipped In

Wet ice

概要

AT 1001 is a high-affinity and selective antagonist of the α3β4 nicotinic acetylcholine receptor ( α3β4 nAChR ) ( K i =2.64 nM). AT 1001 reversibly blocks inward currents induced by Epibatidine in HEK cells transfected with α3β4 nAChR. AT-1001 dose-dependently inhibits nicotine self-administration behavior in rats without affecting food-reinforced responding. AT 1001 can be utilized in the research of nicotine addiction and smoking cessation therapies.

Specifications

仕様と純度

≥99%

保管条件

Store at 2-8°C

入荷

Wet ice

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

アクションタイプ

ANTAGONIST

純度

≥99%

名前と識別子

カノニカル・スマイル

CN1C2CCCC1CC(C2)NC3=CC=CC=C3Br

IUPAC Name

N-(2-bromophenyl)-9-methyl-9-azabicyclo[3.3.1]nonan-3-amine

InChIKey

UZJWAFOJOSGEKL-UHFFFAOYSA-N

INCHI

1S/C15H21BrN2/c1-18-12-5-4-6-13(18)10-11(9-12)17-15-8-3-2-7-14(15)16/h2-3,7-8,11-13,17H,4-6,9-10H2,1H3

異性体SMILES

CN1C2CCCC1CC(C2)NC3=CC=CC=C3Br

PubChem CID

53302872