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AZD 2066 hydrate , CAS No.A659396
AVAILABLE TO ORDER
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
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Why this grade
for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
AZD 2066 hydrate is a selective, orally active and brain-penetrant antagonist of mGluR5 . AZD 2066 hydrate has antinociception effects.
Appearance:Solid
IC50& Target:mGluR5
In Vitro:AZD 2066 (1-10 μM) inhibits Ca 2+ response, with IC 50 s of 27.2±9.1, 3.56±0.52, 96.2±17.8, and 380±78.0 nM in mGlu5/HEK cells and striatal, hippocampal, and cortical cultures respectively. AZD 2066 (1-10 μM) inhibits the oscillatory Ca 2+ response w
In Vivo:AZD 2066 (0.03-30mg/kg; p.o.) shows discriminative effects in rats. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Male Wistar rats (weighing 240-250 g)Dosage: 0.03, 0.1, 0.3, 1, 3,
Biological Activity:AZD 2066 hydrate is a selective, orally active and brain-penetrant antagonist of mGluR5 . AZD 2066 hydrate has antinociception effects.
Specifications
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
ANTAGONIST
Names and Identifiers
| Molecular Weight | 386.33 |
|---|
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Solution Calculators
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