AZD1979 - 10mM in DMSO , CAS No.1254035-84-1

CAS: 1254035-84-1 Cat. No.: A655186 分子式: C₂₅H₂₆N₄O₅ 分子量: 462.50 PubChem CID: 49801838

グレード＆純度 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

概要

AZD1979 is a Melanin-concentrating hormone receptor 1 ( MCHr1 ) antagonist with an IC 50 of ~12 nM.

In Vivo

In DIO mice, initial AZD1979-mediate body weight loss is driven by decreasing food intake, but an additional component of preserving energy expenditure is apparent in pair-feeding and indirect calorimetry studies. AZD1979 also dose-dependently reduces body weight in dogs . MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:IC50: ~12 nM (MCHr1)

仕様

仕様と純度

10mM in DMSO

生化学的・生理学的メカニズム

AZD1979 is a Melanin-concentrating hormone receptor 1 ( MCHr1 ) antagonist with an IC 50 of ~12 nM.

保管条件

Store at -80°C

入荷

Dry ice packs + Cold packs

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

アクションタイプ

ANTAGONIST

名前と識別子

異性体SMILES

COC1=CC=C(C=C1)C2=NN=C(O2)C(=O)N3CC(C3)OC4=CC=C(C=C4)CN5CC6(C5)COC6

代替CAS番号

1254035-84-1

PubChem CID

49801838

MeSH用語

(3-(4-(2-oxa-6-azaspiro(3.3)heptan-6-ylmethyl)phenoxy)azetidin-1-yl)(5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl)methanone;AZD1979

分子量

462.50

関連ターゲット（人間）

MCHR1 Tchem Melanin-concentrating hormone receptor 1 (1 Activities)

Discover Target: MCHR1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

よくある質問

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.