AZD5904 - Moligand™, 10mM in DMSO , Inhibitor of myeloperoxidase, CAS No.618913-30-7, Inhibitor of myeloperoxidase

CAS: 618913-30-7 Cat. No.: A656636 分子式: C₁₀H₁₂N₄O₂S 分子量: 252.29 EC番号: 642-433-3 PubChem CID: 10264211

GRADE & PURITY Moligand™, 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

概要

AZD5904 is a selective and irreversible inhibitor of human Myeloperoxidase ( MPO ) with an IC 50 of 140 nM and has similar potency in mouse and rat.

In Vitro

AZD5904 is a pselective and irreversible inhibitor of human Myeloperoxidase (MPO) with an IC 50 of 140 nM and has similar potency in mouse and rat. It is 10 to 19-fold selective compare to the closely related lactoperoxidase and thyroid peroxidase; >70-fold to a broad panel of other enzymes, ion channels, and receptors. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:IC50: 140 nM (human MPO)

Specifications

仕様と純度

Moligand™, 10mM in DMSO

生化学的・生理学的メカニズム

AZD5904 is a selective and irreversible inhibitor of human Myeloperoxidase ( MPO ) with an IC 50 of 140 nM and has similar potency in mouse and rat.

保管条件

Store at -80°C

入荷

Dry ice packs + Cold packs

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

等級

Moligand™

アクションタイプ

INHIBITOR

作用メカニズム

Inhibitor of myeloperoxidase

名前と識別子

• 異性体SMILES: C1C[C@@H](OC1)CN2C3=C(C(=O)NC2=S)NC=N3
• 代替CAS番号: 618913-30-7
• PubChem CID: 10264211
• 分子量: 252.29

関連ターゲット（人間）

MPO Tchem Myeloperoxidase (1 Activities)

Discover Target: MPO

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)