Balixafortide TFA - Moligand™, ≥98% , CAS No.1051366-32-5(free base)

CAS: 1051366-32-5(free base) Cat. No.: B658810 分子式: C₈₄H₁₁₈N₂₄O₂₁S₂(free base) 分子量: 1864.11(free base)

GRADE & PURITY Moligand™, ≥98%

Synonyms

POL6326 TFA

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

概要

Balixafortide TFA (POL6326 TFA) is a potent, selective, well-tolerated peptidic CXCR4 antagonist with an IC 50 < 10 nM. Balixafortide TFA shows 1000-fold selective for CXCR4 than a large panel of receptors including CXCR7 . Balixafortide TFA blocks β-arre

Appearance:Solid

IC50& Target:CXCR4 <10 nM (IC 50 )

In Vitro:Balixafortide potently inhibits pERK / pAKT signaling in the lymphoma lines Namalwa (IC 50 < 200 nM) and Jurkat (IC 50 < 400 nM). Balixafortide efficiently blocks SDF-1 dependent chemotaxis of MDA MB 231 breast cancer cells (IC 50 < 20 nM), Namalwa and Ju

In Vivo:Balixafortide is optimized for favorable mouse absorption, distribution, metabolism and excretion (ADME) properties with balanced plasma protein binding, greater plasma and microsomal stability. MCE has not independently confirmed the accuracy of the

Biological Activity:Balixafortide TFA (POL6326 TFA) is a potent, selective, well-tolerated peptidic CXCR4 antagonist with an IC 50 < 10 nM. Balixafortide TFA shows 1000-fold selective for CXCR4 than a large panel of receptors including CXCR7 . Balixafortide TFA blocks β-arre

Specifications

同義語

POL6326 TFA

仕様と純度

Moligand™, ≥98%

保管条件

Protected from light,Store at -20°C,Argon charged

入荷

Ice chest + Ice pads

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

等級

Moligand™

アクションタイプ

ANTAGONIST

純度

≥98%

名前と識別子

分子量

1864.11(free base)

化学的性質と物理的性質

• 溶解度: H2O : 100 mg/mL (50.55 mM; Need ultrasonic) DMSO : 100 mg/mL (50.55 mM; Need ultrasonic)
• 感度: Light sensitive；Moisture sensitive