BAY-4931 - ≥98% , CAS No.423150-91-8

CAS: 423150-91-8 Cat. No.: B649506 分子式: C₂₂H₁₆ClN₃O₄ 分子量: 421.83

GRADE & PURITY ≥98%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

概要

BAY-4931 is a potent, covalent and selective PPARγ inverse-agonist with an IC 50 of 0.17 nM

In Vitro

BAY-4931 (0-10 μM; 7 days) inhibits UM-UC-9 proliferation with an IC 50 of 3.4 nM. BAY-4931 only inhibits CYP2C8 in CYP inhibition test. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Proliferation AssayCell Line: UM-UC-9 cells Concentration: 0-10 μM Incubation Time: 7 days Result: Inhibited proliferation with an IC 50 of 3.4 nM.

Form:Solid

IC50& Target:PPAR-γ 0.17 nM (IC 50 , RT112-FABP4-NLucP cellular reporter assay) mouse PPARγ 0.14 nM (IC 50 , GAL4-NHR-LBD one hybrid reporter assay ) hPPARγ 0.40 nM (IC 50 , GAL4-NHR-LBD one hybrid reporter assay )

Specifications

仕様と純度

≥98%

生化学的・生理学的メカニズム

BAY-4931 is a potent, covalent and selective PPARγ inverse-agonist with an IC 50 of 0.17 nM.

保管条件

Store at -20°C

入荷

Ice chest + Ice pads

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

アクションタイプ

ANTAGONIST

純度

≥98%

名前と識別子

• 分子量: 421.83

化学的性質と物理的性質

• 溶解度: DMSO : 125 mg/mL (296.33 mM; ultrasonic and warming and heat to 70°C)