BM-1244 (APG-1252-M1) is a potent Bcl-xL / Bcl-2 inhibitor with K i s of 134 and 450 nM for Bcl- xL and Bcl-2 , respectively. BM-1244 inhibits senescent fibroblasts (SnCs) with an EC 50 of 5 nM. (From patent WO2019033119A1).
Form:Solid
仕様
仕様と純度
≥98%
生化学的・生理学的メカニズム
BM-1244 (APG-1252-M1) is a potent Bcl-xL / Bcl-2 inhibitor with K i s of 134 and 450 nM for Bcl- xL and Bcl-2 , respectively. BM-1244 inhibits senescent fibroblasts (SnCs) with an EC 50 of 5 nM. (From patent WO2019033119A1).
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