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BMS-665053 , CAS No.1173435-64-7
AVAILABLE TO ORDER
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
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Why this grade
for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
BMS-665053 is a corticotropin-releasing factor-1 (CRF1) receptor antagonist ( IC 50 = 1.0 nM). BMS-665053)11 is a potent inhibitor of CRF-stimulated cyclic adenosine monophosphate (cAMP) production in human Y-79 retinoblastoma cells ( IC 50 = 4.9 nM).
Specifications
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
ANTAGONIST
Names and Identifiers
| Canonical Smiles | CC(C1CC1)N2C=C(N=C(C2=O)NC3=C(C=C(C=C3Cl)C(F)(F)F)Cl)Cl |
|---|---|
| IUPAC Name | 5-chloro-1-(1-cyclopropylethyl)-3-[2,6-dichloro-4-(trifluoromethyl)anilino]pyrazin-2-one |
| InChIKey | SQKXWTQRMQRCRW-UHFFFAOYSA-N |
| INCHI | 1S/C16H13Cl3F3N3O/c1-7(8-2-3-8)25-6-12(19)23-14(15(25)26)24-13-10(17)4-9(5-11(13)18)16(20,21)22/h4-8H,2-3H2,1H3,(H,23,24) |
| Isomeric SMILES | CC(C1CC1)N2C=C(N=C(C2=O)NC3=C(C=C(C=C3Cl)C(F)(F)F)Cl)Cl |
| PubChem CID | 56671385 |
| Molecular Weight | 426.6 |
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
3D Structure
Interactive Chemical Structure Model
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Solution Calculators
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Customer Reviews
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