(+)-Borneol - Moligand™, 10mM in DMSO , Activator of TRPV3, CAS No.464-43-7, Activator of TRPV3

CAS: 464-43-7 Cat. No.: B424091 分子式: C₁₀H₁₈O 分子量: 154.25 Beilstein Registry Number: 2038056 EC番号: 207-352-6

GRADE & PURITY Moligand™, 10mM in DMSO

Synonyms

AC-5982 | BS-42578 | D-BORNEOL [WHO-DD] | Pain relief patch-acupoint pressure stimulation | (1R-endo)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-ol | BORNEOL, D- | BRN 2038056 | Endo-2-camphanol | endo-1,7,7-Trimethylbicyclo | (1R-endo)-1,7,7-Trimethylbicyclo(

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

概要

(+)-Borneol, a bicyclic monoterpene, is found in the essential oils of medicinal plants and is commonly used in traditional Chinese medicine for analgesia and anaesthesia.
(+)-Borneol has been used to study its antiapoptotic, antioxidative and neuroprotective effect in human neuroblastoma cells (SH-SY5Y).

Specifications

同義語

AC-5982 | BS-42578 | D-BORNEOL [WHO-DD] | Pain relief patch-acupoint pressure stimulation | (1R-endo)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-ol | BORNEOL, D- | BRN 2038056 | Endo-2-camphanol | endo-1,7,7-Trimethylbicyclo | (1R-endo)-1,7,7-Trimethylbicyclo(

仕様と純度

Moligand™, 10mM in DMSO

保管条件

Store at -80°C

入荷

Dry ice packs + Cold packs

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

等級

Moligand™

アクションタイプ

ACTIVATOR

作用メカニズム

Activator of TRPV3

名前と識別子

• パブケム・シド: 528752690
• 異性体SMILES: C[C@@]12CC[C@@H](C1(C)C)C[C@@H]2O
• WGKドイツ: 3
• RTECS: ED7060000
• UN番号: 1312
• 包装グループ: III
• 分子量: 154.25
• Beilstein: 2038056
• Reaxy-Rn: 6052111
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=6052111&ln=

関連ターゲット（人間）

TRPV3 Tchem Transient receptor potential cation channel subfamily V member 3 (1 Activities)

Discover Target: TRPV3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

関連ターゲット（非人間）

Colletotrichum fragariae (147 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Colletotrichum gloeosporioides (560 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

作用メカニズム

化学的性質と物理的性質

• 比旋光度［α］: +36°, c = 5 in ethanol
• 引火点（°F）: 149 °F
• 引火点（°C）: 65 °C
• 融点（°C）: 206-209°C
• 分子量: 154.250 g/mol
• XLogP3: 2.700
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 154.136 Da
• Monoisotopic Mass: 154.136 Da
• Topological Polar Surface Area: 20.200 Ų
• Heavy Atom Count: 11
• Formal Charge: 0
• Complexity: 185.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 3
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

参考文献

1. Huijuan Li, Xinghui Song, Huiru Li, Lifei Zhu, Shengbo Cao, Jifeng Liu.  (2022)  Sesquiterpenes and Monoterpenes from the Leaves and Stems of Illicium simonsii and Their Antibacterial Activity.  MOLECULES,  27  (3): (1115).  [PMID:35164380] [10.3390/molecules27031115]

2. Jingwei Liu, Tong Shu, Yiheng Mu, Wanlin Zheng, Xiaohuan Lu, Hong Tao.  (2025)  Curdione combined with borneol treats bacterial mixed HPV infection by regulating the crosstalk among immune cells.  Frontiers in Immunology,      [PMID:39911394] [10.3389/fimmu.2025.1503355]