Name: BW-B 70C - Moligand™, ≥98%(HPLC) , Inhibitor of 5-LOX, CAS No.134470-38-5, Inhibitor of 5-LOX
SKU: B288192
Availability: InStock

BW-B 70C - Moligand™, ≥98%(HPLC) , Inhibitor of 5-LOX, CAS No.134470-38-5, Inhibitor of 5-LOX

CAS: 134470-38-5 Cat. No.: B288192 分子式: C₁₇H₁₇FN₂O₃ 分子量: 316.33

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BW-B 70C - Moligand™, ≥98%(HPLC) CAS No(134470-38-5) by Aladdin Scientific

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注文可能

GRADE & PURITY Moligand™ ? ≥98%(HPLC)

Synonyms

BRD-A55946879-001-02-9 | BW B70C | NCGC00025102-06 | 1-{(3E)-4-[3-(4-fluorophenoxy)phenyl]but-3-en-2-yl}-1-hydroxyurea | BRD-A68891053-001-01-2 | BW B70C, >98% (HPLC), solid | N-(3-(3-(4-fluorophenoxy)phenyl)-1-methylprop-2-enyl)-N-hydroxyurea | NCGC00025

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

概要 Specifications 名前と識別子 Documentation Advanced Data Taxonomic Classification 3 D構造関連ターゲット（人間）関連ターゲット（非人間）作用メカニズム証明書（CoA、COO、BSE/TSEと分析図）化学的性質と物理的性質よくある質問と記事ソリューション計算機レビュー

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Why this grade

Moligand™, ≥98%(HPLC) Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -20°C,Argon charged Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

概要

BW B70C is a potent and selective acid 5-lipoxygenase inhibitor. BW B70C inhibits both acute and allergic bronchoconstriction and late-phase eosinophil accumulation subsequent to allergen inhalation in guinea-pigs. BW B70C prevents leukotriene C4 synthesis and reduces leucocyte migration to the airways lumen as well as albumin microvascular leakage. BW B70C has the potential for the research of anti-asthma agent.

Specifications

同義語

仕様と純度

Moligand™, ≥98%(HPLC)

生化学的・生理学的メカニズム

Potent and selective inhibitor of 5-lipoxygenase. Long half-life and high oral bioavailabilityin vivo.

保管条件

Store at -20°C,Argon charged

入荷

Ice chest + Ice pads

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

等級

Moligand™

アクションタイプ

INHIBITOR

作用メカニズム

Inhibitor of 5-LOX

純度

≥98%(HPLC)

名前と識別子

カノニカル・スマイル	CC(C=CC1=CC(=CC=C1)OC2=CC=C(C=C2)F)N(C(=O)N)O
IUPAC Name	1-[(E)-4-[3-(4-fluorophenoxy)phenyl]but-3-en-2-yl]-1-hydroxyurea
InChIKey	UAIYNMRLUHHRMF-AATRIKPKSA-N
INCHI	1S/C17H17FN2O3/c1-12(20(22)17(19)21)5-6-13-3-2-4-16(11-13)23-15-9-7-14(18)8-10-15/h2-12,22H,1H3,(H2,19,21)/b6-5+
異性体SMILES	CC(/C=C/C1=CC(=CC=C1)OC2=CC=C(C=C2)F)N(C(=O)N)O
WGKドイツ	3
RTECS	YT3976666
分子量	316.33
Reaxy-Rn	23687444
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=23687444&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Benzenoids
  - 分類 Benzene and substituted derivatives
    - Subclass Diphenylethers

Kingdom	Organic compounds
Superclass	Benzenoids
分類	Benzene and substituted derivatives
Subclass	Diphenylethers
Intermediate Tree Nodes	Not available
Direct Parent	Diphenylethers
Alternative Parents	Diarylethers Styrenes Phenoxy compounds Phenol ethers Fluorobenzenes Aryl fluorides Organic carbonic acids and derivatives Organopnictogen compounds Organonitrogen compounds Organofluorides Organic oxides Hydrocarbon derivatives Carbonyl compounds
Molecular Framework	Aromatic homomonocyclic compounds
Substituents	Diphenylether - Diaryl ether - Phenoxy compound - Styrene - Phenol ether - Fluorobenzene - Halobenzene - Aryl fluoride - Aryl halide - Carbonic acid derivative - Ether - Organofluoride - Organohalogen compound - Organooxygen compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Carbonyl group - Organic oxygen compound - Organic nitrogen compound - Organonitrogen compound - Aromatic homomonocyclic compound
説明	This compound belongs to the class of organic compounds known as diphenylethers. These are aromatic compounds containing two benzene rings linked to each other through an ether group.
External Descriptors	organofluorine compound - aromatic ether - ureas - hydroxamic acid
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

3 D構造

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レビュー

Need help choosing the grade?

Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

View Moligand™ grade guide →

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溶解度	Solvent:ethanol, Max Conc. mg/mL: None, Max Conc. mM: 3; Solvent:DMSO, Max Conc. mg/mL: None, Max Conc. mM: 3
融点（°C）	>134°C (dec.)
分子量	316.330 g/mol
XLogP3	2.800
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	5
Exact Mass	316.122 Da
Monoisotopic Mass	316.122 Da
Topological Polar Surface Area	75.800 Å²
Heavy Atom Count	23
Formal Charge	0
Complexity	411.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	1
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	1
Covalently-Bonded Unit Count	1