Capreomycin sulfate - Potency 700 - 1050 μG/mg , CAS No.1405-37-4

CAS: 1405-37-4 Cat. No.: C117924 分子式: C₂₅H₄₄N₁₄O₇.H₂SO₄ 分子量: 750.78 EC番号: 215-776-8 PubChem CID: 22836615

GRADE & PURITY Potency 700 - 1050 μG/mg

Synonyms

CCG-270439 | AKOS025310793 | CAPREOMYCINSULFATE | A911135 | CAPREOMYCIN, SULFATE (SALT) | (2S)-2,5-Diamino-N-(((2S,5S,11S,15S,Z)-15-amino-11-(2-amino-3,4,5,6-tetrahydropyrimidin-4-yl)-2-(hydroxymethyl)-3,6,9,12,16-pentaoxo-8-(ureidomethylene)-1,4,7,10,13-

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

概要

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Specifications

同義語

CCG-270439 | AKOS025310793 | CAPREOMYCINSULFATE | A911135 | CAPREOMYCIN, SULFATE (SALT) | (2S)-2,5-Diamino-N-(((2S,5S,11S,15S,Z)-15-amino-11-(2-amino-3,4,5,6-tetrahydropyrimidin-4-yl)-2-(hydroxymethyl)-3,6,9,12,16-pentaoxo-8-(ureidomethylene)-1,4,7,10,13-

仕様と純度

Potency 700 - 1050 μG/mg

生化学的・生理学的メカニズム

Cyclic peptide antibiotic thought to inhibit protein synthesis by binding to the 70S ribosomal unit. Disrupts interaction of Mycobacterium tuberculosis ribosomal proteins L12 and L10.

保管条件

Store at -20°C

入荷

Ice chest + Ice pads

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

注

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

名前と識別子

パブケム・シド

528774079

カノニカル・スマイル

C1CN=C(NC1C2C(=O)NCC(C(=O)NC(C(=O)NC(C(=O)NC(=CNC(=O)N)C(=O)N2)CNC(=O)C(CCCN)N)CO)N)N.OS(=O)(=O)O

IUPAC Name

(2S)-2,5-diamino-N-[[(2S,5S,8Z,11S,15S)-15-amino-11-(2-amino-1,4,5,6-tetrahydropyrimidin-6-yl)-8-[(carbamoylamino)methylidene]-2-(hydroxymethyl)-3,6,9,12,16-pentaoxo-1,4,7,10,13-pentazacyclohexadec-5-yl]methyl]pentanamide;sulfuric acid

InChIKey

LFFNIXQXRKNZCE-XYHGUWSSSA-N

INCHI

1S/C24H42N14O8.H2O4S/c25-4-1-2-10(26)17(40)32-7-13-19(42)34-14(8-33-24(29)46)20(43)38-16(12-3-5-30-23(28)37-12)22(45)31-6-11(27)18(41)36-15(9-39)21(44)35-13;1-5(2,3)4/h8,10-13,15-16,39H,1-7,9,25-27H2,(H,31,45)(H,32,40)(H,34,42)(H,35,44)(H,36,41)(H,38,43)(H3,28,30,37)(H3,29,33,46);(H2,1,2,3,4)/b14-8-;/t10-,11-,12?,13-,15-,16-;/m0./s1

異性体SMILES

C1CN=C(NC1[C@H]2C(=O)NC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N/C(=C\NC(=O)N)/C(=O)N2)CNC(=O)[C@H](CCCN)N)CO)N)N.OS(=O)(=O)O

WGKドイツ

3

RTECS

EX8930000

PubChem CID

22836615

分子量

750.78

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • 分類 Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Peptides
          • Level6 Oligopeptides

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• 分類: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Peptides
• Direct Parent: Oligopeptides
• Alternative Parents: Cyclic peptides Macrolactams Alpha amino acid amides Beta amino acids and derivatives Organic sulfuric acids N-acyl amines Hydropyrimidines Vinylogous amides Secondary carboxylic acid amides Ureas Guanidines Lactams Propargyl-type 1,3-dipolar organic compounds Azacyclic compounds Carboximidamides Primary alcohols Carbonyl compounds Organic oxides Monoalkylamines Hydrocarbon derivatives
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: Alpha-oligopeptide - Cyclic alpha peptide - Macrolactam - Alpha-amino acid amide - Beta amino acid or derivatives - Alpha-amino acid or derivatives - Sulfuric acid - Fatty amide - Fatty acyl - Hydropyrimidine - 1,4,5,6-tetrahydropyrimidine - N-acyl-amine - Vinylogous amide - Organic sulfuric acid or derivatives - Urea - Secondary carboxylic acid amide - Amino acid or derivatives - Carboxamide group - Guanidine - Lactam - Azacycle - Organoheterocyclic compound - Carboximidamide - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Primary alcohol - Primary amine - Hydrocarbon derivative - Organonitrogen compound - Carbonyl group - Organic oxide - Organooxygen compound - Alcohol - Organic nitrogen compound - Organic oxygen compound - Primary aliphatic amine - Amine - Aliphatic heteromonocyclic compound
• 説明: This compound belongs to the class of organic compounds known as oligopeptides. These are organic compounds containing a sequence of between three and ten alpha-amino acids joined by peptide bonds.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

化学的性質と物理的性質

• 溶解度: Freely soluble in water
• 沸点（°C）: 1377℃
• 分子量: 752.800 g/mol
• Hydrogen Bond Donor Count: 16
• Hydrogen Bond Acceptor Count: 16
• Rotatable Bond Count: 9
• Exact Mass: 752.298 Da
• Monoisotopic Mass: 752.298 Da
• Topological Polar Surface Area: 461.000 Ų
• Heavy Atom Count: 51
• Formal Charge: 0
• Complexity: 1310.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 5
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 1
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 1
• Covalently-Bonded Unit Count: 2

XLogP3