CB2R/FAAH modulator-3 - ≥99% , CAS No.2876918-67-9

CAS: 2876918-67-9 Cat. No.: C646918 分子式: C₂₂H₃₁NO₂ 分子量: 341.49

GRADE & PURITY ≥99%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

概要

CB2R/FAAH modulator-3 (compound 27) is a dual targeting modulator that acts as a CB2R agonist and FAAH inhibitor. The K i values for CB2R/FAAH modulator-3 are 20.1 and 67.6 nM for CB2R and CB1R, respectively, and the IC 50 value for FAAH is 3.4 μM. CB2R/FAAH modulator-3 can be used in studies related to cancer , deleterious inflammatory cascades occurring in neurodegenerative diseases, and COVID-19 infection

In Vitro

CB2R/FAAH modulator-3 (compound 27)(10 μM) reduces the production of the pro-inflammatory cytokines TNFα, IFN-γ, IL-1β and IL6 in unstimulated monocytes and macrophages. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:CB1 67.6 nM (Ki) CB2 20.1 nM (Ki)

Specifications

仕様と純度

≥99%

生化学的・生理学的メカニズム

CB2R/FAAH modulator-3 (compound 27) is a dual targeting modulator that acts as a CB2R agonist and FAAH inhibitor. The K i values for CB2R/FAAH modulator-3 are 20.1 and 67.6 nM for CB2R and CB1R, respectively, and the IC 50 value for FAAH is 3.4 μM. CB2R/F

保管条件

Store at -20°C

入荷

Ice chest + Ice pads

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

アクションタイプ

AGONIST

純度

≥99%

名前と識別子

• 分子量: 341.49

化学的性質と物理的性質

• 溶解度: DMSO : 50 mg/mL (146.42 mM; Need ultrasonic)