CCF0058981 - 10mM in DMSO , CAS No.C661647(DMSO)

CAS: C661647(DMSO) Cat. No.: C661647 分子式: C₂₄H₁₉ClN₆O 分子量: 442.9

GRADE & PURITY 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

概要

CCF0058981 (CCF981), 3-chlorophenyl analogue, is a noncovalent SARS-CoV-2 3CL pro (SC2) inhibitor with an IC 50 of 68 nM. CCF0058981 inhibits SC1 (SARS-CoV-1 3CL pro ) with an IC 50 of 19 nM. CCF0058981 has antiviral efficacy and has the potential for COV

IC50& Target:IC50: 68 nM (SC2) and 19 nM (SC1)

In Vitro:CCF0058981 (CCF981) has cytopathic effect (CPE) inhibition (EC 50 =497 nM) and plaque reduction (EC 50 =558 nM) in vitro viral replication. CCF0058981 has the 50% cytotoxic concentration (CC 50 ) in the CPE antiviral assay of >50 μM. CCF0058981

Biological Activity:CCF0058981 (CCF981), 3-chlorophenyl analogue, is a noncovalent SARS-CoV-2 3CL pro (SC2) inhibitor with an IC 50 of 68 nM. CCF0058981 inhibits SC1 (SARS-CoV-1 3CL pro ) with an IC 50 of 19 nM. CCF0058981 has antiviral efficacy and has the potential for COV

Specifications

仕様と純度

10mM in DMSO

保管条件

Store at -80°C

入荷

Dry ice packs + Cold packs

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

名前と識別子

カノニカル・スマイル

O=C(N(C1=CC=C(C2=CNC=N2)C=C1)CC3=CC=CC(Cl)=C3)CN4N=NC5=CC=CC=C54

分子量

442.9