cGAMP (Cyclic GMP-AMPP) diammonium functions as an endogenous second messenger in metazoans and triggers interferon production in response to cytosolic DNA. cGAMP diammonium activates stimulator of interferon genes (STING) , which activates a signaling ca
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IC50& Target:Human Endogenous Metabolite
In Vitro:cGAMP diammonium promotes the antigen-specific proliferation capacity of spleen cells in mice. cGAMP diammonium directly activates murine and human dendritic cells in vitro. On stimulation with cGAMP diammonium, fibroblasts from the patients sho
In Vivo:cGAMP (5 µg; nostril mucosal adjuvant) diammonium promotes the antigen-specific cytokine production by spleen cells of immunized mice. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Femal
Biological Activity:cGAMP (Cyclic GMP-AMPP) diammonium functions as an endogenous second messenger in metazoans and triggers interferon production in response to cytosolic DNA. cGAMP diammonium activates stimulator of interferon genes (STING) , which activates a signaling ca
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What is the purity of this product?
This product is supplied at ≥95% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.
How should this product be stored?
Store at ?20 °C, desiccated. Keep the container tightly closed with desiccant — the material is moisture-sensitive.
How is this product shipped?
This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is C659108, the molecular formula is C20H30N12O13P2, and the molecular weight is 708.47 g/mol.
What documentation is provided?
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