CHAPS hydrate - UltraBio™, Ultra pure, ≥98% , CAS No.331717-45-4

CAS: 331717-45-4 Cat. No.: C475301 分子式: C₃₂H₅₈N₂O₇S · xH₂O 分子量: 614.88 (anhydrous basis) EC番号: 695-474-4

GRADE & PURITY UltraBio™, Ultra pure, ≥98%

Synonyms

3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate hydrate | CHAPS

Storage

Room temperature

概要

CHAPS is a non-denaturing, zwitterionic sulfobetaine detergent. It is mild and solubilizes membrane proteins and receptors. It is useful for breaking protein-protein interactions. It is a derivative of the naturally occurring bile salts. It has small micellar molecular weight (6,150) and high critical micellar concentration (6 - 10 mM) allowing it to be removed from samples by dialysis.10mM CHAPS detergent has been used in the process of ion-exchange chromatography for improved purification.0.5 w/v of CHAPS is a component of high salt buffer in protein purification alongside HEPES, NaCl and EDTA.HEPES buffer has been used as lysis buffer in immunoprecipitation, supplemented with 1% CHAPS.

Specifications

同義語

3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate hydrate | CHAPS

仕様と純度

UltraBio™, Ultra pure, ≥98%

保管条件

Room temperature

等級

Ultra pure, UltraBio™

純度

≥98%

名前と識別子

• カノニカル・スマイル: CC(CCC(=O)NCCC[N+](C)(C)CCCS(=O)(=O)[O-])C1CCC2C1(C(CC3C2C(CC4C3(CCC(C4)O)C)O)O)C.O
• IUPAC Name: 3-[dimethyl-[3-[[(4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]propyl]azaniumyl]propane-1-sulfonate;hydrate
• InChIKey: SJCUTFKCLFLIFE-JWTJKVBLSA-N
• INCHI: 1S/C32H58N2O7S.H2O/c1-21(8-11-29(38)33-14-6-15-34(4,5)16-7-17-42(39,40)41)24-9-10-25-30-26(20-28(37)32(24,25)3)31(2)13-12-23(35)18-22(31)19-27(30)36;/h21-28,30,35-37H,6-20H2,1-5H3,(H-,33,38,39,40,41);1H2/t21-,22+,23-,24-,25+,26+,27-,28+,30+,31+,32-;/m1./s1
• 異性体SMILES: C[C@H](CCC(=O)NCCC[N+](C)(C)CCCS(=O)(=O)[O-])[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)O)C.O
• WGKドイツ: 1
• 代替CAS番号: 75621-03-3
• 分子量: 614.88 (anhydrous basis)

化学的性質と物理的性質

• 溶解度: H2O: 0.1M, clear, colorless

参考文献

1. Li Guanglei, Chen Yao, Liu Fei, Bi Wenhua, Wang Chenxin, Lu Danfeng, Wen Dan.  (2023)  Portable visual and electrochemical detection of hydrogen peroxide release from living cells based on dual-functional Pt-Ni hydrogels.  Microsystems & Nanoengineering,  9  (1): (1-10).  [PMID:38033990] [10.1038/s41378-023-00623-y]

2. Jie Zhao, Shuaiqian Wang, Diandian Jiang, Yan Lu, Yu Chen, Yong Tang, Jie Tang, Zhenju Jiang, Hongbin Lin, Wei Dong.  (2023)  Unravelling the interaction between α-SOH and myofibrillar protein based on spectroscopy and molecular dynamics simulation.  Food Chemistry-X,      [PMID:38144868] [10.1016/j.fochx.2023.100986]

3. Zhe Chen, Yunxia Wang.  (2023)  A label- and enzyme-free fluorescence assay based on thioflavin T–induced G-quadruplexes for the detection of telomerase activity.  JOURNAL OF CHEMICAL RESEARCH,      [PMID:] [10.1177/17475198221139085]

4. Pengfei Dong, Longyi Zhu, Jing Huang, Jujie Ren, Jianping Lei.  (2019)  Electrocatalysis of cerium metal-organic frameworks for ratiometric electrochemical detection of telomerase activity.  BIOSENSORS & BIOELECTRONICS,      [PMID:31108380] [10.1016/j.bios.2019.05.018]

5. Min Zhang, Chong-sheng Peng, Xiao-bo Li.  (2017)  Human intestine and liver microsomal metabolic differences between C19-diester and monoester diterpenoid alkaloids from the roots of Aconitum carmichaelii Debx..  TOXICOLOGY IN VITRO,      [PMID:28919359] [10.1016/j.tiv.2017.09.011]

6. Feifei Gong, Huaxin Yang, Wen Sun, Junzi Cao, Wanhui Liu.  (2015)  Development and validation of a micellar electrokinetic capillary chromatography method for the determination of goserelin and related substances.  ELECTROPHORESIS,  37  (4): (623-629).  [PMID:26635325] [10.1002/elps.201500328]