Clindamycin palmitate HCl - ≥99% , Bacterial 70S ribosome inhibitor, CAS No.25507-04-4, Bacterial 70S ribosome inhibitor

CAS: 25507-04-4 Cat. No.: E129339 分子式: C₃₄H₆₃ClN₂O₆S·HCl 分子量: 699.85 EC番号: 607-740-9 PubChem CID: 16052038

GRADE & PURITY ≥99%

Synonyms

CLINDAMYCIN PALMITATE HYDROCHLORIDE [USP-RS] | (2R,3r,4s,5r,6r)-6-((1s,2s)-2-chloro-1-((2s,4r)-1-methyl-4-propylpyrrolidine-2-carboxamido)propyl)-4,5-dihydroxy-2-(methylthio)tetrahydro-2h-pyran-3-yl palmitate | DTXCID0028660 | CJB32966 | CLINDAMYCIN PALMI

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

概要

Clindamycin palmitate HCl is a water soluble hydrochloride salt of the ester of clindamycin and palmitic acid and a lincosamide antibiotic.

Specifications

同義語

CLINDAMYCIN PALMITATE HYDROCHLORIDE [USP-RS] | (2R,3r,4s,5r,6r)-6-((1s,2s)-2-chloro-1-((2s,4r)-1-methyl-4-propylpyrrolidine-2-carboxamido)propyl)-4,5-dihydroxy-2-(methylthio)tetrahydro-2h-pyran-3-yl palmitate | DTXCID0028660 | CJB32966 | CLINDAMYCIN PALMI

仕様と純度

≥99%

生化学的・生理学的メカニズム

Clindamycin palmitate HCl is a water soluble hydrochloride salt of the ester of clindamycin and palmitic acid and a lincosamide antibiotic. Clindamycin palmitate HCl is a bacterial protein synthesis inhibitor by inhibiting ribosomal translocation, in a si

保管条件

Store at -20°C

入荷

Ice chest + Ice pads

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

アクションタイプ

INHIBITOR

作用メカニズム

Bacterial 70S ribosome inhibitor

注

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

純度

≥99%

名前と識別子

• パブケム・シド: 488199027
• パブケム・シド・ウル: https://pubchem.ncbi.nlm.nih.gov/substance/488199027
• カノニカル・スマイル: CCCCCCCCCCCCCCCC(=O)OC1C(C(C(OC1SC)C(C(C)Cl)NC(=O)C2CC(CN2C)CCC)O)O.Cl
• IUPAC Name: [(2R,3R,4S,5R,6R)-6-[(1S,2S)-2-chloro-1-[[(2S,4R)-1-methyl-4-propylpyrrolidine-2-carbonyl]amino]propyl]-4,5-dihydroxy-2-methylsulfanyloxan-3-yl] hexadecanoate;hydrochloride
• InChIKey: GTNDZRUWKHDICY-DJHAJVGHSA-N
• INCHI: 1S/C34H63ClN2O6S.ClH/c1-6-8-9-10-11-12-13-14-15-16-17-18-19-21-27(38)42-32-30(40)29(39)31(43-34(32)44-5)28(24(3)35)36-33(41)26-22-25(20-7-2)23-37(26)4;/h24-26,28-32,34,39-40H,6-23H2,1-5H3,(H,36,41);1H/t24-,25+,26-,28+,29+,30-,31+,32+,34+;/m0./s1
• 異性体SMILES: CCCCCCCCCCCCCCCC(=O)O[C@@H]1[C@H]([C@H]([C@H](O[C@@H]1SC)[C@@H]([C@H](C)Cl)NC(=O)[C@@H]2C[C@H](CN2C)CCC)O)O.Cl
• PubChem CID: 16052038
• 分子量: 699.85

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic oxygen compounds
    • 分類 Organooxygen compounds
      • Subclass Carbohydrates and carbohydrate conjugates
        • Level5 Glycosyl compounds
          • Level6 Thioglycosides

• Kingdom: Organic compounds
• Superclass: Organic oxygen compounds
• 分類: Organooxygen compounds
• Subclass: Carbohydrates and carbohydrate conjugates
• Intermediate Tree Nodes: Glycosyl compounds
• Direct Parent: Thioglycosides
• Alternative Parents: Fatty acid esters Oxanes Monosaccharides N-alkylpyrrolidines Monothioacetals Trialkylamines 1,2-diols Secondary alcohols Amino acids and derivatives Carboxylic acid esters Sulfenyl compounds Propargyl-type 1,3-dipolar organic compounds Azacyclic compounds Carboximidic acids Oxacyclic compounds Monocarboxylic acids and derivatives Carbonyl compounds Organopnictogen compounds Hydrocarbon derivatives Hydrochlorides Alkyl chlorides Organochlorides Organic oxides
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: S-glycosyl compound - Fatty acid ester - Monosaccharide - Oxane - Fatty acyl - N-alkylpyrrolidine - Monothioacetal - Pyrrolidine - 1,2-diol - Amino acid or derivatives - Carboxylic acid ester - Secondary alcohol - Tertiary amine - Tertiary aliphatic amine - Carboximidic acid - Carboximidic acid derivative - Carboxylic acid derivative - Monocarboxylic acid or derivatives - Oxacycle - Azacycle - Organoheterocyclic compound - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Sulfenyl compound - Alkyl halide - Alkyl chloride - Hydrocarbon derivative - Organic oxide - Amine - Organohalogen compound - Organochloride - Organonitrogen compound - Organosulfur compound - Hydrochloride - Organopnictogen compound - Carbonyl group - Organic nitrogen compound - Alcohol - Aliphatic heteromonocyclic compound
• 説明: This compound belongs to the class of organic compounds known as thioglycosides. These are glycoside in which a sugar group is bonded through one carbon to another group via a S-glycosidic bond.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

作用メカニズム

化学的性質と物理的性質

• 溶解度: DMSO 140 mg/mL Water 140 mg/mL Ethanol 140 mg/mL
• 分子量: 699.900 g/mol
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 23
• Exact Mass: 698.386 Da
• Monoisotopic Mass: 698.386 Da
• Topological Polar Surface Area: 134.000 Ų
• Heavy Atom Count: 45
• Formal Charge: 0
• Complexity: 810.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 9
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3