CO23 - ≥98% , CAS No.1370363-74-8

CAS: 1370363-74-8 Cat. No.: C649591 分子式: C₁₉H₁₈I₂N₂O₄ 分子量: 592.17

GRADE & PURITY ≥98%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

概要

CO23 is a selective thyroid hormone receptor (TR) α agonist and used for growth and development regulation. CO23 was able to be transported through the blood-brain barrier

In Vivo

CO23 (ip; 0.04-5.0 nmol/g) has ≈50% cholesterol reduction with 0.8 nmol/g dose and higher doses are equally effective. CO23 has no effect at the lowest dose of 0.04 nmol/g and increases Dio1 mRNA 5-, 10-, and 15-fold at the doses of 0.8, 2.5, and 5 nmol/g, respectively . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Hypothyroid Wistar rats Dosage: 0.04, 0.8, 2.5, and 5.0 nmol/g Administration: Ip Result: Had ≈50% cholesterol reduction with 0.8 nmol/g dose and higher doses were equally effective.

Form:Solid

IC50& Target:TRα

Specifications

仕様と純度

≥98%

生化学的・生理学的メカニズム

CO23 is a selective thyroid hormone receptor (TR) α agonist and used for growth and development regulation. CO23 was able to be transported through the blood-brain barrier.

保管条件

Store at -20°C

入荷

Ice chest + Ice pads

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

アクションタイプ

AGONIST

純度

≥98%

名前と識別子

• 分子量: 592.17

化学的性質と物理的性質

• 溶解度: DMSO : 250 mg/mL (422.18 mM; Need ultrasonic)