COG 133 TFA - ≥98% , CAS No.C658607

CAS: C658607 Cat. No.: C658607 分子式: C₉₉H₁₈₂F₃N₃₇O₂₁ 分子量: 2283.78

グレード＆純度 ≥98%

Storage

Desiccated,Store at -80°C

Shipped In

Dry ice packs + Cold packs

概要

COG 133 TFA is a fragment of Apolipoprotein E (APOE) peptide. COG 133 TFA competes with the ApoE holoprotein for binding the LDL receptor, with potent anti-inflammatory and neuroprotective effects. COG 133 TFA is also a nAChR antagonist with an IC 50 of 4

Appearance:Solid

IC50& Target:IC50: 445 nM (nAChR)

In Vivo:COG 133 (1mg/kg; intratracheal administration; every other day; for 4 weeks) treatment impairs the resolution of pulmonary fibrosis in mice. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model

Biological Activity:COG 133 TFA is a fragment of Apolipoprotein E (APOE) peptide. COG 133 TFA competes with the ApoE holoprotein for binding the LDL receptor, with potent anti-inflammatory and neuroprotective effects. COG 133 TFA is also a nAChR antagonist with an IC 50 of 4

仕様

仕様と純度

≥98%

保管条件

Desiccated,Store at -80°C

入荷

Dry ice packs + Cold packs

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

アクションタイプ

ANTAGONIST

純度

≥98%

名前と識別子

分子量

2283.78

化学的性質と物理的性質

• 溶解度: H2O : 50 mg/mL (21.89 mM; Need ultrasonic)