Colchiceine - Moligand™, ≥98% , CAS No.477-27-0

CAS: 477-27-0 Cat. No.: X614895 Molecular Weight: 385.41 EC Number: 207-512-5 PubChem CID: 234105

COA

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Colchiceine - Moligand™, ≥98% CAS No(477-27-0) by Aladdin Scientific

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AVAILABLE TO ORDER

GRADE & PURITY Moligand™ ? ≥98%

Synonyms

COLCHICEINE|477-27-0|O10-Demethylcolchicine|colchicein|N-Acetyl trimethylcolchicinic acid|NSC33411|NSC 33411|Coichiceine|O-Demethylcolchicine|Colchiceine (VAN)|O(sup 10)-Demethylcolchicine|UNII-HJ30158L57|EINECS 207-512-5|NSC-33411|HJ30158L57|NSC 123396|N

Storage

Store at 2-8°C

Shipped In

Wet ice

Overview Specifications Names and Identifiers Documentation Advanced Data Taxonomic Classification 3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solution Calculators Reviews

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Why this grade

Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Colchiceine is one of several metabolites of the anti-gout medication Colchicine. Colchicine is a tubulin inhibitor and a microtubule disrupting agent, and may protect rats from developing liver injury and fibrosis

Specifications

Synonyms

COLCHICEINE | 477-27-0 | O10-Demethylcolchicine | colchicein | N-Acetyl trimethylcolchicinic acid | NSC33411 | NSC 33411 | Coichiceine | O-Demethylcolchicine | Colchiceine (VAN) | O(sup 10)-Demethylcolchicine | UNII-HJ30158L57 | EINECS 207-512-5 | NSC-33411 | HJ30158L57 | NSC 123396 | N

Specifications & Purity

Moligand™, ≥98%

Storage

Store at 2-8°C

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Action Type

INHIBITOR

Purity

≥98%

Names and Identifiers

Canonical Smiles	CC(=O)NC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)O)OC)OC)OC
IUPAC Name	N-[(7S)-10-hydroxy-1,2,3-trimethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
InChIKey	PRGILOMAMBLWNG-HNNXBMFYSA-N
INCHI	1S/C21H23NO6/c1-11(23)22-15-7-5-12-9-18(26-2)20(27-3)21(28-4)19(12)13-6-8-16(24)17(25)10-14(13)15/h6,8-10,15H,5,7H2,1-4H3,(H,22,23)(H,24,25)/t15-/m0/s1
Isomeric SMILES	CC(=O)N[C@H]1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)O)OC)OC)OC
PubChem CID	234105
Molecular Weight	385.41

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Hydrocarbon derivatives
  - Class Tropones
    - Subclass Tropolones

Kingdom	Organic compounds
Superclass	Hydrocarbon derivatives
Class	Tropones
Subclass	Tropolones
Intermediate Tree Nodes	Not available
Direct Parent	Tropolones
Alternative Parents	Anisoles Alkyl aryl ethers Acetamides Secondary carboxylic acid amides Cyclic ketones Organopnictogen compounds Organonitrogen compounds Organic oxides
Molecular Framework	Aromatic homopolycyclic compounds
Substituents	Tropolone - Anisole - Alkyl aryl ether - Benzenoid - Acetamide - Carboxamide group - Secondary carboxylic acid amide - Cyclic ketone - Ether - Carboxylic acid derivative - Organic oxygen compound - Organooxygen compound - Organonitrogen compound - Organic nitrogen compound - Carbonyl group - Organopnictogen compound - Organic oxide - Aromatic homopolycyclic compound
Description	This compound belongs to the class of organic compounds known as tropolones. These are compounds containing tropone ring with a hydroxyl group at ring position 2.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

3D Structure

Associated Targets(Human)

BRD4 Tchem Bromodomain-containing protein 4 (1 Activities)

Discover Target: BRD4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GLP1R Tclin Glucagon-like peptide 1 receptor (111429 Activities)

Discover Target: GLP1R

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TUBB1 Tclin Tubulin beta-1 chain (182 Activities)

Discover Target: TUBB1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)

Discover Target: CYP2C9

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

A498 (42825 Activities)

Lot Number	Certificate Type	Date	Item
G2517478	Certificate of Analysis	Feb 08, 2025	X614895
G2517553	Certificate of Analysis	Feb 08, 2025	X614895
G2517554	Certificate of Analysis	Feb 08, 2025	X614895
G2517555	Certificate of Analysis	Feb 08, 2025	X614895
G2517556	Certificate of Analysis	Feb 08, 2025	X614895
G2517557	Certificate of Analysis	Feb 08, 2025	X614895

Molecular Weight	385.400 g/mol
XLogP3	1.200
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	4
Exact Mass	385.153 Da
Monoisotopic Mass	385.153 Da
Topological Polar Surface Area	94.100 Å²
Heavy Atom Count	28
Formal Charge	0
Complexity	724.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Colchiceine - Moligand™, ≥98% , CAS No.477-27-0

Why this grade

Storage & shipping

Quality documents

Literature proof

Overview

Specifications

Documentation

📋 Safety Data Sheet (SDS)

✅ Certificate of Analysis (COA)

📊 Datasheet

🔬 Specification Sheet

Advanced Data

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

Customer Reviews

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