Cortagine - ≥99% , CAS No.C658697

CAS: C658697 Cat. No.: C658697 分子式: C₁₉₂H₃₂₃N₅₅O₆₃S 分子量: 4442.06

グレード＆純度 ≥99%

Storage

Desiccated,Store at -80°C

Shipped In

Dry ice packs + Cold packs

概要

Cortagine is a specific corticotropin-releasing factor receptor subtype 1 (CRF1) agonist with an EC 50 of 2.6 nM for rCRF1. Cortagine is an anxiolytic and antidepressive agent in the mouse model.

Appearance:Solid

IC50& Target:CRFR1

In Vitro:Cortagine inhibits rCRF1 (EC 50 =0.18 nM) and mCRF 2β (EC 50 =16 nM) in transfected HEK-293 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo:Cortagine (30, 100, 300 ng; i.c.v.) significantly decreases the percent time spent in the open arms and number of open arm entries of the elevated plus-maze (EPM) test in nine-week-old male C57BL/6J mice. MCE has not independently confirmed the accur

Biological Activity:Cortagine is a specific corticotropin-releasing factor receptor subtype 1 (CRF1) agonist with an EC 50 of 2.6 nM for rCRF1. Cortagine is an anxiolytic and antidepressive agent in the mouse model.

仕様

仕様と純度

≥99%

保管条件

Desiccated,Store at -80°C

入荷

Dry ice packs + Cold packs

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

アクションタイプ

AGONIST

純度

≥99%

名前と識別子

分子量

4442.06

化学的性質と物理的性質

• 溶解度: DMSO : 50 mg/mL (11.26 mM; Need ultrasonic)

よくある質問

What is the purity of this product?

This product is supplied at ≥99% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?80 °C, desiccated. Keep the container tightly closed with desiccant — the material is moisture-sensitive.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is C658697, the molecular formula is C192H323N55O63S, and the molecular weight is 4442.06 g/mol.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.