Corticosterone - Moligand™, ≥98% , Agonist of Glucocorticoid receptor;Agonist of Mineralocorticoid receptor, CAS No.50-22-6, Agonist of Glucocorticoid receptor;Agonist of Mineralocorticoid receptor

Name: Corticosterone - Moligand™, ≥98% , Agonist of Glucocorticoid receptor;Agonist of Mineralocorticoid receptor, CAS No.50-22-6, Agonist of Glucocorticoid receptor;Agonist of Mineralocorticoid receptor
SKU: C104537
Availability: InStock

CAS: 50-22-6 Cat. No.: C104537 分子式: C₂₁H₃₀O₄ 分子量: 346.46 Beilstein Registry Number: 2339601 EC番号: 200-019-6

59 Citations COA

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Corticosterone - Moligand™, ≥98% CAS No(50-22-6) by Aladdin Scientific

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注文可能

GRADE & PURITY Moligand™ ? ≥98%

Synonyms

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

概要 Specifications 名前と識別子 Documentation Advanced Data Taxonomic Classification 3 D構造関連ターゲット（人間）関連ターゲット（非人間）作用メカニズム証明書（CoA、COO、BSE/TSEと分析図）化学的性質と物理的性質よくある質問と記事 Citations of This Product ソリューション計算機レビュー

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Why this grade

Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -20°C,Argon charged Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 59 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

概要

Corticosterone, the major stress hormone, is an adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid.
Corticosteroid is an activator of MCR.

Specifications

同義語

仕様と純度

Moligand™, ≥98%

生化学的・生理学的メカニズム

Endogenous glucocorticoid that acts as an agonist at glucocorticoid and mineralocorticoid receptors.

保管条件

Store at -20°C,Argon charged

入荷

Ice chest + Ice pads

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

等級

Moligand™

アクションタイプ

AGONIST

作用メカニズム

Agonist of Glucocorticoid receptor;Agonist of Mineralocorticoid receptor

純度

≥98%

名前と識別子

パブケム・シド

528773721

カノニカル・スマイル

CC12CCC(=O)C=C1CCC3C2C(CC4(C3CCC4C(=O)CO)C)O

IUPAC Name

(8S,9S,10R,11S,13S,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one

InChIKey

OMFXVFTZEKFJBZ-HJTSIMOOSA-N

INCHI

1S/C21H30O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)21(15,2)10-17(24)19(14)20/h9,14-17,19,22,24H,3-8,10-11H2,1-2H3/t14-,15-,16+,17-,19+,20-,21-/m0/s1

異性体SMILES

C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@H]4C(=O)CO)C)O

WGKドイツ

RTECS

GM7650000

分子量

346.46

Beilstein

2339601

Reaxy-Rn

2063664

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2063664&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Lipids and lipid-like molecules
  - 分類 Steroids and steroid derivatives
    - Subclass Hydroxysteroids

Kingdom	Organic compounds
Superclass	Lipids and lipid-like molecules
分類	Steroids and steroid derivatives
Subclass	Hydroxysteroids
Intermediate Tree Nodes	Not available
Direct Parent	21-hydroxysteroids
Alternative Parents	Gluco/mineralocorticoids, progestogins and derivatives 20-oxosteroids 3-oxo delta-4-steroids 11-beta-hydroxysteroids Delta-4-steroids Cyclohexenones Alpha-hydroxy ketones Secondary alcohols Cyclic alcohols and derivatives Primary alcohols Organic oxides Hydrocarbon derivatives
Molecular Framework	Aliphatic homopolycyclic compounds
Substituents	Progestogin-skeleton - 21-hydroxysteroid - Pregnane-skeleton - 20-oxosteroid - 3-oxo-delta-4-steroid - 3-oxosteroid - 11-hydroxysteroid - 11-beta-hydroxysteroid - Oxosteroid - Delta-4-steroid - Cyclohexenone - Alpha-hydroxy ketone - Cyclic alcohol - Ketone - Secondary alcohol - Cyclic ketone - Hydrocarbon derivative - Organic oxide - Carbonyl group - Organic oxygen compound - Alcohol - Organooxygen compound - Primary alcohol - Aliphatic homopolycyclic compound
説明	This compound belongs to the class of organic compounds known as 21-hydroxysteroids. These are steroids carrying a hydroxyl group at the 21-position of the steroid backbone.
External Descriptors	C21 steroids (gluco/mineralocorticoids, progestogins) and derivatives
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

3 D構造

関連ターゲット（非人間）

ERG2 C-8 sterol isomerase (237 Activities)

Discover Target: ERG2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Sigmar1 Sigma opioid receptor (160 Activities)

Discover Target: Sigmar1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Abcb1b P-glycoprotein 1 (174 Activities)

Discover Target: Abcb1b

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mapk1 MAP kinase ERK2 (650 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Nr1i3 Constitutive androstane receptor (427 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Shbg Testis-specific androgen-binding protein (10 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Hdac6 Histone deacetylase 6 (222 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Galc Galactocerebrosidase (11 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Pseudomonas aeruginosa (123386 Activities)

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Klebsiella pneumoniae (43867 Activities)

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Staphylococcus aureus (210822 Activities)

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Acinetobacter baumannii (41033 Activities)

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Escherichia coli (133304 Activities)

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Plasmodium falciparum (966862 Activities)

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Cryptococcus neoformans (21258 Activities)

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Candida albicans (78123 Activities)

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Mus musculus (284745 Activities)

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Rattus norvegicus (775804 Activities)

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rep Replicase polyprotein 1ab (378 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Slc22a6 Solute carrier family 22 member 6 (141 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Slc22a5 Solute carrier family 22 member 5 (44 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Rorc Nuclear receptor ROR-gamma (89407 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NS1 Nonstructural protein 1 (33327 Activities)

Discover Target: NS1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Nr1i2 Nuclear receptor subfamily 1 group I member 2 (14 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Slc22a3 Solute carrier family 22 member 3 (35 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Slco1a1 Solute carrier organic anion transporter family member 1A1 (265 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Slco1a4 Solute carrier organic anion transporter family member 1A4 (114 Activities)

Discover Target: Slco1a4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Abcb1a P-glycoprotein 1 and 3 (MDR1a/MDR1b) (23 Activities)

Discover Target: Abcb1a

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

作用メカニズム

証明書（CoA、COO、BSE/TSEと分析図）

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

41 results found

Lot Number	Certificate Type	日付	商品
A2630362	Certificate of Analysis	Jan 15, 2026	C104537
A2630363	Certificate of Analysis	Jan 15, 2026	C104537
A2630374	Certificate of Analysis	Jan 15, 2026	C104537
A2630376	Certificate of Analysis	Jan 15, 2026	C104537
A2521127	Certificate of Analysis	Jan 11, 2025	C104537
A2521130	Certificate of Analysis	Jan 11, 2025	C104537
A2521131	Certificate of Analysis	Jan 11, 2025	C104537
A2521138	Certificate of Analysis	Jan 11, 2025	C104537
F2516057	Certificate of Analysis	Jan 11, 2025	C104537
L2418788	Certificate of Analysis	Nov 30, 2024	C104537
A2510169	Certificate of Analysis	Nov 30, 2024	C104537
L2418787	Certificate of Analysis	Nov 30, 2024	C104537
L2418784	Certificate of Analysis	Nov 30, 2024	C104537
L2418775	Certificate of Analysis	Nov 30, 2024	C104537
J2408328	Certificate of Analysis	Sep 19, 2024	C104537
J2408327	Certificate of Analysis	Sep 19, 2024	C104537
J2408326	Certificate of Analysis	Sep 19, 2024	C104537
G2425158	Certificate of Analysis	Jul 05, 2024	C104537
G2425159	Certificate of Analysis	Jul 05, 2024	C104537
G2425160	Certificate of Analysis	Jul 05, 2024	C104537
G2425161	Certificate of Analysis	Jul 05, 2024	C104537
D2424132	Certificate of Analysis	Apr 10, 2024	C104537
D2424133	Certificate of Analysis	Apr 10, 2024	C104537
H2324224	Certificate of Analysis	Aug 03, 2023	C104537
H2324183	Certificate of Analysis	Aug 03, 2023	C104537
H2324219	Certificate of Analysis	Aug 03, 2023	C104537
H2324222	Certificate of Analysis	Aug 03, 2023	C104537
H2307598	Certificate of Analysis	Jul 11, 2023	C104537
B2302921	Certificate of Analysis	Dec 30, 2022	C104537
B2302817	Certificate of Analysis	Dec 30, 2022	C104537
B2302957	Certificate of Analysis	Dec 30, 2022	C104537
B2302878	Certificate of Analysis	Dec 30, 2022	C104537
I2202249	Certificate of Analysis	Jul 20, 2022	C104537
I2202250	Certificate of Analysis	Jul 20, 2022	C104537
I2202251	Certificate of Analysis	Jul 20, 2022	C104537
I2202252	Certificate of Analysis	Jul 20, 2022	C104537
G2208130	Certificate of Analysis	Jan 08, 2022	C104537
B2207303	Certificate of Analysis	Jan 08, 2022	C104537
B2207302	Certificate of Analysis	Jan 08, 2022	C104537
B2207301	Certificate of Analysis	Jan 08, 2022	C104537
B2207300	Certificate of Analysis	Jan 08, 2022	C104537

化学的性質と物理的性質

溶解度	Solvent:DMSO, Max Conc. mg/mL: 34.65, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 3.46, Max Conc. mM: 10
感度	Hygroscopic
比旋光度［α］	+221 to +226 deg(C=1, EtOH)
融点（°C）	180-183°C
分子量	346.500 g/mol
XLogP3	1.900
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	2
Exact Mass	346.214 Da
Monoisotopic Mass	346.214 Da
Topological Polar Surface Area	74.600 Å²
Heavy Atom Count	25
Formal Charge	0
Complexity	638.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	7
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

よくある質問と記事

Glucocorticoids (GCs) and the Glucocorticoid Receptor (GR): Mechanisms, Classification Frameworks, and the Latest Advances (with a Product Selection Table)

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

Glucocorticoids GCs Glucocorticoid Receptor (GR) GR

Neurosteroids and Protective Mechanisms in the Central Nervous System

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

neuroinflammation neurosteroids central nervous system neuroprotection pregnenolone progesterone allopregnanolone remyelination

Frequently asked Questions about inhibitors and antagonists related products（FAQ）

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

inhibitor FAQ Antagonists Frequently asked questions Instructions

Citations of This Product

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レビュー

📚 Citations by Application

Other applications22

Organic synthesis — reaction medium14

Drug / compound screening29

Cell viability20

Cell proliferation8

Cytotoxicity screening22

Chromatography (HPLC / GC / TLC)6

Extraction & workup solvent6

Electrochemistry & battery electrolyte2

Spectroscopy sample preparation2

Cancer cell line characterization2

Polymer synthesis & polymerization1

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Corticosterone - Moligand™, ≥98% , Agonist of Glucocorticoid receptor;Agonist of Mineralocorticoid receptor, CAS No.50-22-6, Agonist of Glucocorticoid receptor;Agonist of Mineralocorticoid receptor

Storage & shipping

Quality documents

Literature proof

概要

Specifications

Documentation

📋 Safety Data Sheet (SDS)

✅ Certificate of Analysis (COA)

📊 Datasheet

🔬 Specification Sheet

Advanced Data

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

顧客レビュー

📚 Citations by Application

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関連商品

Corticosterone - Moligand™, ≥98% , Agonist of Glucocorticoid receptor;Agonist of Mineralocorticoid receptor, CAS No.50-22-6, Agonist of Glucocorticoid receptor;Agonist of Mineralocorticoid receptor

Storage & shipping

Quality documents

Literature proof

概要

Specifications

Documentation

📋 Safety Data Sheet (SDS)

✅ Certificate of Analysis (COA)

📊 Datasheet

🔬 Specification Sheet

Advanced Data

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

顧客レビュー

📚 Citations by Application

Need help choosing the grade?

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