CVN424 - 10mM in DMSO , CAS No.2254706-21-1

CAS: 2254706-21-1 Cat. No.: C656045 分子式: C₂₄H₂₉F₂N₅O₃ 分子量: 473.52 EC番号: 192-146-8 PubChem CID: 137359492

GRADE & PURITY 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

概要

CVN424 is an orally active and selective GPR6 inverse agonist with a K i of 9.4 nM and an EC 50 of 38 nM. CVN424 is brain-penetrant and has the potential for Parkinson disease research

In Vitro

CVN424 (Compound 6i) has 265 fold and 68 fold selectivities over GPR3 and GPR12. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:Ki: 9.4 nM (GPR6), EC50: 38 nM (GPR6)

Specifications

仕様と純度

10mM in DMSO

生化学的・生理学的メカニズム

CVN424 is an orally active and selective GPR6 inverse agonist with a K i of 9.4 nM and an EC 50 of 38 nM. CVN424 is brain-penetrant and has the potential for Parkinson disease research.

保管条件

Store at -80°C

入荷

Dry ice packs + Cold packs

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

名前と識別子

• 異性体SMILES: CC(=O)N1CCC2=C(C1)N=C(C(=N2)N3CCC(CC3)OC4=C(C=C(C=C4)F)F)N[C@@H]5CCOC5
• 代替CAS番号: 2254706-21-1
• PubChem CID: 137359492
• 分子量: 473.52

関連ターゲット（人間）

GPR6 Tchem G-protein coupled receptor 6 (4 Activities)

Discover Target: GPR6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 (2 Activities)

Discover Target: KCNH2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)