Cy5.5 - ≥97% , CAS No.210892-23-2

CAS: 210892-23-2 Cat. No.: C651516 Molecular Weight: 917.05 PubChem CID: 131875897
AVAILABLE TO ORDER
GRADE & PURITY ≥97%
Synonyms
Sulfo-Cyanine5.5
Storage
Protected from light,Store at -20°C
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
1mg
C651516-1mg
1
$46.90
5mg
C651516-5mg
1
$159.90
10mg
C651516-10mg
1
$269.90
25mg
C651516-25mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$529.90
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Why this grade

≥97% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Protected from light,Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 19 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Cy5.5 (Sulfo-Cyanine5.5) is a near-infrared fluorescent dye for labeling biomolecules such as peptides, proteins and oligonucleotides.

Specifications

Synonyms
Sulfo-Cyanine5.5
Specifications & Purity
≥97%
Biochemical and Physiological Mechanisms
Cy5.5 is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coeffic
Storage
Protected from light, Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Purity
≥97%
Names and Identifiers
Canonical SmilesCCN1C2=C(C3=C(C=C2)C(=CC(=C3)S(=O)(=O)O)S(=O)(=O)[O-])C(C1=CC=CC=CC4=[N+](C5=C(C4(C)C)C6=C(C=C5)C(=CC(=C6)S(=O)(=O)O)S(=O)(=O)O)CCCCCC(=O)O)(C)C
IUPAC Name(2E)-2-[(2E,4E)-5-[3-(5-carboxypentyl)-1,1-dimethyl-6,8-disulfobenzo[e]indol-3-ium-2-yl]penta-2,4-dienylidene]-3-ethyl-1,1-dimethyl-8-sulfobenzo[e]indole-6-sulfonate
InChIKeyLIZDKDDCWIEQIN-UHFFFAOYSA-N
INCHI1S/C41H44N2O14S4/c1-6-42-31-18-16-27-29(21-25(58(46,47)48)23-33(27)60(52,53)54)38(31)40(2,3)35(42)13-9-7-10-14-36-41(4,5)39-30-22-26(59(49,50)51)24-34(61(55,56)57)28(30)17-19-32(39)43(36)20-12-8-11-15-37(44)45/h7,9-10,13-14,16-19,21-24H,6,8,11-12,15,20H2,1-5H3,(H4-,44,45,46,47,48,49,50,51,52,53,54,55,56,57)
PubChem CID 131875897
MeSH Entry Terms CY5.5;CY5.5 cyanine dye
Molecular Weight 917.05

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClassNaphthalenes
SubclassNaphthalene sulfonic acids and derivatives
Intermediate Tree Nodes Naphthalene sulfonates
Direct Parent2-naphthalene sulfonates
Alternative Parents 1-naphthalene sulfonates  1-naphthalene sulfonic acids and derivatives  2-naphthalene sulfonic acids and derivatives  3-alkylindoles  1-sulfo,2-unsubstituted aromatic compounds  Tertiary alkylarylamines  Medium-chain fatty acids  Heterocyclic fatty acids  Sulfonyls  Organosulfonic acids  Amino acids  Carboxylic acid salts  Carboxylic acids  Azacyclic compounds  Propargyl-type 1,3-dipolar organic compounds  Monocarboxylic acids and derivatives  Enamines  Organic salts  Carbonyl compounds  Organic oxides  Hydrocarbon derivatives  Organic cations  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents 2-naphthalene sulfonate - 1-naphthalene sulfonate - 2-naphthalene sulfonic acid or derivatives - 1-naphthalene sulfonic acid or derivatives - 3-alkylindole - Arylsulfonic acid or derivatives - Indole or derivatives - 1-sulfo,2-unsubstituted aromatic compound - Tertiary aliphatic/aromatic amine - Medium-chain fatty acid - Heterocyclic fatty acid - Fatty acyl - Organic sulfonic acid or derivatives - Organosulfonic acid or derivatives - Organosulfonic acid - Sulfonyl - Amino acid or derivatives - Carboxylic acid salt - Amino acid - Tertiary amine - Propargyl-type 1,3-dipolar organic compound - Organoheterocyclic compound - Azacycle - Organic 1,3-dipolar compound - Carboxylic acid derivative - Carboxylic acid - Enamine - Monocarboxylic acid or derivatives - Organic salt - Hydrocarbon derivative - Organonitrogen compound - Organic oxide - Organic oxygen compound - Organooxygen compound - Organosulfur compound - Amine - Carbonyl group - Organic nitrogen compound - Organic cation - Aromatic heteropolycyclic compound
DescriptionThis compound belongs to the class of organic compounds known as 2-naphthalene sulfonates. These are organic aromatic compounds that contain a naphthalene moiety that carries a sulfonic acid group at the 2-position. Naphthalene is a bicyclic compound that is made up of two fused benzene ring.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

21 results found

Lot NumberCertificate TypeDateItem
C2510083Certificate of AnalysisDec 10, 2025 C651516
C2510085Certificate of AnalysisDec 10, 2025 C651516
C2510086Certificate of AnalysisDec 10, 2025 C651516
C2620144Certificate of AnalysisNov 26, 2025 C651516
L2504258Certificate of AnalysisNov 26, 2025 C651516
L2504257Certificate of AnalysisNov 26, 2025 C651516
L2504256Certificate of AnalysisNov 26, 2025 C651516
L2504255Certificate of AnalysisNov 26, 2025 C651516
F2603070Certificate of AnalysisNov 26, 2025 C651516
E2626024Certificate of AnalysisNov 26, 2025 C651516
A2629042Certificate of AnalysisNov 26, 2025 C651516
G2507545Certificate of AnalysisJul 11, 2025 C651516
G2517302Certificate of AnalysisJul 11, 2025 C651516
G2517303Certificate of AnalysisJul 11, 2025 C651516
G2517304Certificate of AnalysisJul 11, 2025 C651516
C2510084Certificate of AnalysisFeb 26, 2025 C651516
C2510082Certificate of AnalysisFeb 26, 2025 C651516
C2510081Certificate of AnalysisFeb 26, 2025 C651516
C2409211Certificate of AnalysisFeb 23, 2024 C651516
C2409209Certificate of AnalysisFeb 23, 2024 C651516
C2409210Certificate of AnalysisFeb 23, 2024 C651516

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Chemical and Physical Properties
SolubilityDMSO : 100 mg/mL (109.05 mM; Need ultrasonic) H2O : 5 mg/mL (5.45 mM; ultrasonic and warming and heat to 60°C)
SensitivityLight sensitive
Documents & Articles
Citations of This Product
References
1. Wang Haoyu, Li Lei, Cao Xinran, Zhen Mingming, Wang Chunru, Bai Chunli.  (2023)  Application of mannose-modified fullerene immunomodulator selectively polarizes tumor-associated macrophages potentiating antitumor immunity.  Nano Research,  16  (11): (12855-12863).  [PMID:] [10.1007/s12274-023-6266-x]
2. Xianyang Li, Jingyuan Huang, Xin Wu, Xianling Piao, Danning Lv, Gude Zhang, Dong June Ahn, Chunzhi Cui.  (2023)  Obviously Enhanced Fluorescent Signal of Core-Shell Nanostructures through Simultaneous Regulation of Spectral Overlap and Shell Thickness for Imaging and Photothermal Therapy of Ovarian Cancer Cells.  PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION,      [PMID:] [10.1002/ppsc.202300083]
3. Meng Xu, Haidong Zha, Jiamao Chen, Simon Ming-Yuen Lee, Qi Wang, Ruibing Wang, Ying Zheng.  (2023)  “Ice & Fire” Supramolecular Cell-Conjugation Drug Delivery Platform for Deep Tumor Ablation and Boosted Anti-Tumor Immunity.  ADVANCED MATERIALS,      [PMID:37547984] [10.1002/adma.202305287]
4. Mingqiao Li, Hedan Xu, Nan Zhao, Liangjun Zhang, Haihan Xia, Xiaoxun Zhang, Qiao Li, Min Liao, Qiong Pan, Zeng Yi, Jin Chai.  (2023)  Hepatocyte-targeted hyaluronic acid-polyethyleneimine conjugates for acute liver injury therapy by ROS elimination and inflammation modulation.  MATERIALS & DESIGN,      [PMID:] [10.1016/j.matdes.2023.112212]
5. Xuzi Cai, Si Shi, Gui Chen, Min Zhong, Yuanyuan Yang, Ziyi Mai, Yang Tian, Jinxiu Tan, Lijuan He, Chunhui Cui, Zhiqiang Yu, Xuefeng Wang.  (2022)  Glutamine metabolism targeting liposomes for synergistic chemosensitization and starvation therapy in ovarian cancer.  Acta Biomaterialia,      [PMID:36596434] [10.1016/j.actbio.2022.12.052]
6. Meiting Li, Yaqian Zhang, Xiaoge Zhang, Zhuoyin Liu, Junjie Tang, Miao Feng, Baizhu Chen, Dalin Wu, Jie Liu.  (2022)  Degradable Multifunctional Porphyrin-Based Porous Organic Polymer Nanosonosensitizer for Tumor-Specific Sonodynamic, Chemo- and Immunotherapy.  ACS Applied Materials & Interfaces,      [PMID:36281484] [10.1021/acsami.2c14776]
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8. Ying Chen, Zi-Hao Li, Pei Pan, Run-Yao Zeng, Xian-Zheng Zhang.  (2021)  Tumor-Specific ONOO– Nanogenerator for Improved Drug Delivery and Enhanced Chemotherapy of Tumor.  ACS Nano,      [PMID:34275285] [10.1021/acsnano.1c01312]
9. Wang Haijun, Jia Dianlong, Yuan Dandan, Yin Xiaolei, Yuan Fengjiao, Wang Feifei, Shi Wenna, Li Hui, Zhu Li-Min, Fan Qing.  (2021)  Dimeric Her2-specific affibody mediated cisplatin-loaded nanoparticles for tumor enhanced chemo-radiotherapy.  JOURNAL OF NANOBIOTECHNOLOGY,  19  (1): (1-23).  [PMID:33985511] [10.1186/s12951-021-00885-6]
10. Han Wu, Hao Xing, Meng-Chao Wu, Feng Shen, Yu Chen, Tian Yang.  (2021)  Extracellular-vesicles delivered tumor-specific sequential nanocatalysts can be used for MRI-informed nanocatalytic Therapy of hepatocellular carcinoma.  Theranostics,      [PMID:33391461] [10.7150/thno.46124]
11. Hafza Behroz Mehvish, Shirong Zhang, Yi Liang, Da Sun, Xu Qiu, Kai Qu, Xian Qin, Jiawei Li, Fei Yan, Chunhui Lang, Lixin Xu, Guixue Wang, Jian Chen, Bo He, Kun Zhang, Wei Wu.  (2025)  Enhanced Osteoporosis Treatment via Nano Drug Coating Encapsulating Lactobacillus rhamnosus GG.  ACS Applied Materials & Interfaces,      [PMID:39789866] [10.1021/acsami.4c17985]
12. Zihao Wang, Ziming Jiang, Yu Zhang, Congwei Wang, Zhaoyang Liu, Zhankui Jia, Sudhanshu Bhushan, Jinjian Yang, Zhengguo Zhang.  (2024)  Exosomes derived from bladder epithelial cells infected with uropathogenic Escherichia coli increase the severity of urinary tract infections (UTIs) by impairing macrophage function.  PLoS Pathogens,  20  (1): (e1011926).  [PMID:38190378] [10.1371/journal.ppat.1011926]
13. Yunhao Wang, Lei Ding, Ziguo Lin, Baolong Li, Di Hu, Shichen Zhang, Shujun Zhou, Yuxiang Ning, Fei Xin, Yunfei Ying, Fukai Zhu, Peiyuan Wang, Yanfeng Wang.  (2025)  Mesoporous dual-atom nanozyme induced cuproptosis and apoptosis for boosting immunogenic cell death along with reprogramming tumor immune-suppressive microenvironment.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.160294]
14. Ting Wang, Jie Chen, Chuandong Shu, Xinkun Shen, Yuanyuan Fu, Menghuan Li, Zhong Luo.  (2025)  Orally-administrable supramolecular probiotic capsules enable cooperative colon-targeted inflammation inhibition for ameliorating ulcerative colitis.  Acta Biomaterialia,      [PMID:39884521] [10.1016/j.actbio.2025.01.049]
15. Huijiao Fu, Xiaoqiao Guo, Feng Fang, Cao Zhou, Yuanyuan Chen, Xuanbo Zhang, Bingchen Zhang, Xinran Li, Qiwen Liu, Jie Liu, Wei Chen, Ling Yu, Zhiqiang Yu, Xuefeng Wang.  (2025)  STING pathway activation with cisplatin polyprodrug nanoparticles for chemo-immunotherapy in ovarian cancer.  JOURNAL OF CONTROLLED RELEASE,      [PMID:39993638] [10.1016/j.jconrel.2025.02.061]
16. Yaoyu Hu, Pengfei Zhu, Junwei Deng, Yi Yu, Qian Chen, Haitao Wu, Zhengbao Zha, Hua Wang, Yan Ma.  (2025)  Hydrogen Therapy and Lipopolysaccharide Trapping with MgB2@Inulin Gel for Reversing Colitis and Its Associated Psychiatric Complications via the Gut–Brain Axis.  ACS Nano,      [PMID:40700348] [10.1021/acsnano.5c03843]
17. Zhenzhen Feng, Gui Chen, Min Zhong, Ling Lin, Ziyi Mai, Yan Tang, Guimei Chen, Wen Ma, Guang Li, Yuanyuan Yang, Zhiqiang Yu, Meng Yu.  (2023)  An acid-responsive MOF nanomedicine for augmented anti-tumor immunotherapy via a metal ion interference-mediated pyroptotic pathway.  BIOMATERIALS,      [PMID:37738743] [10.1016/j.biomaterials.2023.122333]
18. Yin Xiujuan, Xue Shuqin, Ji Jiaqi, Zhao Mingyu, Shao Min, Yin Likang, Zhang Saisai, Liu Lei, Li Bin, Zhang Lei, Li Yuan, Wang Xiao.  (2025)  Ultrasound-activated dual-nanozyme platform for targeted ROS scavenging and NO delivery in liver fibrosis therapy.  Advanced Composites and Hybrid Materials,  (4): (1-23).  [PMID:] [10.1007/s42114-025-01411-0]
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