Cyclamic acid - Moligand™, 10mM in DMSO , Antagonist of TAS2R31;Antagonist of TAS2R43, CAS No.100-88-9, Antagonist of TAS2R31;Antagonist of TAS2R43

CAS: 100-88-9 Cat. No.: C408450 分子式: C₆H₁₃NO₃S 分子量: 179.24 Beilstein Registry Number: 2208885 EC番号: 202-898-1

グレード＆純度 Moligand™, 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

概要

Information

Cyclamic acid (NSC 220327) in the form of its sodium or calcium salt is one of the most widely used artificial sweeteners.
In vitro

Cyclamic acid in the form of its sodium or calcium salt is one of the most widely used artificial sweeteners in food and pharmaceuticals. Cyclamic acid is in use in more than 50 countries, especially in combination with other sweeteners, to eliminate aftertaste. However, the petition on Cyclamic acid, calcium and sodium cyclamate is being held in abeyance with the FDA in the USA (CFSAN - Office of Food Additive Safety, 2006).

In vivo

Cell Data

cell lines：BaF3.TPR-MET, H69 and H345 cells

Concentrations：

Incubation Time：

Powder Purity:

仕様

仕様と純度

Moligand™, 10mM in DMSO

生化学的・生理学的メカニズム

A non-nutritive sweetener.Potent TAS 1 R 3 ligand. Binds to the transmembrane domain of TAS 1 R 3 . Action is unaffected by umami compounds. Putative carcinogenic agent in vivo. Orally active.

保管条件

Store at -80°C

入荷

Dry ice packs + Cold packs

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

等級

Moligand™

アクションタイプ

ANTAGONIST

作用メカニズム

Antagonist of TAS2R31;Antagonist of TAS2R43

名前と識別子

異性体SMILES

C1CCC(CC1)NS(=O)(=O)O

WGKドイツ

2

RTECS

GV6950000

代替CAS番号

100-88-9

NSC番号

220327

MeSH用語

Calcium Cyclamate;Cyclamate;Cyclamate Calcium (2:1) Salt;Cyclamate, Calcium;Cyclamate, Calcium (2:1) Salt, Dihydrate;Cyclamate, Potassium;Cyclamate, Sodium;Cyclamate, Sodium Salt;Cyclamates;Cyclamic Acid;Potassium Cyclamate;Sodium Cyclamate

分子量

179.24

Beilstein

2208885

Reaxy-Rn

2208885

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2208885&ln=

関連ターゲット（人間）

TAS2R43 Tchem Taste receptor type 2 member 43 (0 Activities)

Discover Target: TAS2R43

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TAS2R31 Tchem Taste receptor type 2 member 31 (0 Activities)

Discover Target: TAS2R31

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

化学的性質と物理的性質

• 融点（°C）: 169 °C(dec.)

よくある質問

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 100-88-9, the molecular formula is C6H13NO3S, and the molecular weight is 179.24 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.