Cytochalasin E - ≥99% , CAS No.36011-19-5

CAS: 36011-19-5 Cat. No.: C1423603 分子式: C₂₈H₃₃NO₇ 分子量: 495.56 Beilstein Registry Number: 1096975 EC番号: 252-835-7 PubChem CID: 5458385

GRADE & PURITY ≥99%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

概要

Cytochalasin E, an epoxide containing Aspergillus -derived fungal metabolite, inhibits angiogenesis and tumor growth. Cytochalasin E is a potent actin depolymerization agent, and it binds and caps the barbed end of actin filaments to prevent actin elongation.

Specifications

仕様と純度

≥99%

保管条件

Store at -20°C

入荷

Ice chest + Ice pads

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

純度

≥99%

名前と識別子

• カノニカル・スマイル: CC1CC=CC2C3C(O3)(C(C4C2(C(=O)NC4CC5=CC=CC=C5)OC(=O)OC=CC(C1=O)(C)O)C)C
• IUPAC Name: (1S,5E,7R,9S,11E,13S,14S,16R,17S,18S,19S)-19-benzyl-7-hydroxy-7,9,16,17-tetramethyl-2,4,15-trioxa-20-azatetracyclo[11.8.0.01,18.014,16]henicosa-5,11-diene-3,8,21-trione
• InChIKey: LAJXCUNOQSHRJO-ZYGJITOWSA-N
• INCHI: 1S/C28H33NO7/c1-16-9-8-12-19-23-27(4,35-23)17(2)21-20(15-18-10-6-5-7-11-18)29-24(31)28(19,21)36-25(32)34-14-13-26(3,33)22(16)30/h5-8,10-14,16-17,19-21,23,33H,9,15H2,1-4H3,(H,29,31)/b12-8+,14-13+/t16-,17-,19-,20-,21-,23-,26+,27+,28+/m0/s1
• 異性体SMILES: C[C@H]1C/C=C/[C@H]2[C@H]3[C@](O3)([C@H]([C@@H]4[C@]2(C(=O)N[C@H]4CC5=CC=CC=C5)OC(=O)O/C=C/[C@@](C1=O)(C)O)C)C
• WGKドイツ: 3
• RTECS: HA5360000
• PubChem CID: 5458385
• 分子量: 495.56
• Beilstein: 1096975

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Alkaloids and derivatives
    • 分類 Cytochalasans

• Kingdom: Organic compounds
• Superclass: Alkaloids and derivatives
• 分類: Cytochalasans
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Cytochalasans
• Alternative Parents: Macrolactams Isoindolones Oxepanes Pyrrolidine-2-ones Acyloins Benzene and substituted derivatives Carbonic acid diesters Tertiary alcohols Enol esters Secondary carboxylic acid amides Cyclic ketones Lactams Oxacyclic compounds Azacyclic compounds Dialkyl ethers Epoxides Organic oxides Organopnictogen compounds Hydrocarbon derivatives Organonitrogen compounds
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Cytoglobosin skeleton - Cytochalasan - Macrolactam - Isoindolone - Isoindoline - Isoindole or derivatives - Oxepane - Monocyclic benzene moiety - Carbonic acid diester - Benzenoid - Acyloin - 2-pyrrolidone - Pyrrolidone - Enol ester - Tertiary alcohol - Pyrrolidine - Carboxamide group - Cyclic ketone - Ketone - Lactam - Secondary carboxylic acid amide - Carbonic acid derivative - Carboxylic acid derivative - Organoheterocyclic compound - Azacycle - Ether - Oxirane - Oxacycle - Dialkyl ether - Organooxygen compound - Organic oxygen compound - Organic nitrogen compound - Alcohol - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Carbonyl group - Organonitrogen compound - Aromatic heteropolycyclic compound
• 説明: This compound belongs to the class of organic compounds known as cytochalasans. These are fungal metabolites structurally characterized by the presence of an isoindolone nucleus fused to a macrocyclic ring, which can either a lactone, as in cytochalasin B, a carbonate, as in cytochalasin E, or a carbocycle, as in cytochalasin D, H, and K.
• External Descriptors: cytochalasan alkaloid

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

よくある質問

What is the purity of this product?

This product is supplied at ≥99% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 36011-19-5, the molecular formula is C28H33NO7, and the molecular weight is 495.56 g/mol. InChIKey LAJXCUNOQSHRJO-ZYGJITOWSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.