Dalpiciclib - Moligand™, ≥98% , Inhibitor of cyclin dependent kinase 4;Inhibitor of cyclin dependent kinase 6, CAS No.1637781-04-4, Inhibitor of cyclin dependent kinase 4;Inhibitor of cyclin dependent kinase 6

CAS: 1637781-04-4 Cat. No.: D609727 分子式: C₂₅H₃₀N₆O₂ 分子量: 446.54

GRADE & PURITY Moligand™, ≥98%

Synonyms

6-acetyl-8-cyclopentyl-5-methyl-2-[(5-piperidin-4-ylpyridin-2-yl)amino]pyrido[2,3-d]pyrimidin-7-one | GTPL11189 | AKOS040759914 | EX-A5817 | Pyrido(2,3-d)pyrimidin-7(8H)-one, 6-acetyl-8-cyclopentyl-5-methyl-2-((5-(4-piperidinyl)-2-pyridinyl)amino)- | DALP

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Specifications

同義語

6-acetyl-8-cyclopentyl-5-methyl-2-[(5-piperidin-4-ylpyridin-2-yl)amino]pyrido[2,3-d]pyrimidin-7-one | GTPL11189 | AKOS040759914 | EX-A5817 | Pyrido(2,3-d)pyrimidin-7(8H)-one, 6-acetyl-8-cyclopentyl-5-methyl-2-((5-(4-piperidinyl)-2-pyridinyl)amino)- | DALP

仕様と純度

Moligand™, ≥98%

生化学的・生理学的メカニズム

Dalpiciclib (SHR-6390) is a highly selective, orally bioavailable, and comparable potency inhibitor of CDK4 and CKD6 with IC50s of 12.4 nM and 9.9 nM, respectively. Dalpiciclib exerts potent antitumor activity in esophageal squamous cell carcinoma by inhi

保管条件

Store at -20°C

入荷

Ice chest + Ice pads

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

等級

Moligand™

アクションタイプ

INHIBITOR

作用メカニズム

Inhibitor of cyclin dependent kinase 4;Inhibitor of cyclin dependent kinase 6

純度

≥98%

名前と識別子

• 分子量: 446.54

関連ターゲット（人間）

CDK4 Tclin Cyclin-dependent kinase 4 (0 Activities)

Discover Target: CDK4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CDK6 Tclin Cyclin-dependent kinase 6 (0 Activities)

Discover Target: CDK6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)