Name: DAMGO - Moligand™, ≥95% , Agonist of κ receptor;Agonist of μ receptor, CAS No.78123-71-4, Agonist of κ receptor;Agonist of μ receptor
Brand: Aladdin Scientific
SKU: D275414
Availability: InStock

DAMGO - Moligand™, ≥95% , Agonist of κ receptor;Agonist of μ receptor, CAS No.78123-71-4, Agonist of κ receptor;Agonist of μ receptor

CAS: 78123-71-4 Cat. No.: D275414 分子式: C₂₆H₃₅N₅O₆ 分子量: 513.59

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DAMGO - Moligand™, ≥95% CAS No(78123-71-4) by Aladdin Scientific

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注文可能

グレード＆純度 Moligand™ ? ≥95%

Synonyms

H-Tyr-D-Ala-Gly-N(Me)Phe-Gly-ol|Tyr-D-Ala-Gly-N(CH3)Phe-Gly-ol|(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]-methylamino]-N-(2-hydroxyethyl)-3-phenylpropanamide|158: PN: US20030176421 PAGE: 54-55 CLAIMED PROTEIN|bicyclo[2.2.1]-5-heptene-2,3-dicarboxylic anhydride|(S)-2-amino-N-((R)-1-(2-(((S)-1-(2-hydroxyethylamino)-1-oxo-3-phenylpropan-2-yl)(methyl)amino)-2-oxoethylamino)-1-oxopropan-2-yl)-3-(4-hydroxyphenyl)propanamide|D-Ala2-MePhe4-Met(0)5-enkephalin-ol|(D-Ala(2)-mephe(4)-gly-ol(5))enkephalin|2-Ala-4-mephe-5-gly-enkephalin|DAMGO|L-Phenylalaninamide, L-tyrosyl-D-alanylglycyl-N-(2-hydroxyethyl)-Nalpha-methyl-|Enkephalin, ala(2)-mephe(4)-gly(5)-|RX783006;Dagol|[D-Ala2, NMe-Phe4, Gly-ol5]-enkephalin|3: PN: WO2009046859 PAGE: 98 CLAIMED PROTEIN|Tyr-D-Ala-Gly-N-Methyl-Phe-Gly-ol|[tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephalin|H-Tyr-D-Ala-Gly-MePhe-Gly-ol|Ala(2)-mephe(4)-gly-ol(5) enkephalin|L-Tyrosyl-D-alanylglycyl-N-(2-hydroxyethyl)-Nalpha-methyl-L-phenylalaninamide|[3H]DAMGO|L-TYROSYL-D-ALANYLGLYCYL-N-(2-HYDROXYETHYL)-N.ALPHA.-METHYL-L-PHENYLALANINAMIDE|Tyr-D-Ala-Gly-(NMe)Phe-Gly-ol|DAGO|DAMGE|(2S)-2-amino-N-[(2R)-1-[[2-[[(2S)-1-(2-hydroxyethylamino)-1-oxo-3-phenylpropan-2-yl]-methylamino]-2-oxoethyl]amino]-1-oxopropan-2-yl]-3-(4-hydroxyphenyl)propanamide|Tyr-D-Ala-Gly-N-Me-Phe-Gly-ol|Tyr-D-Ala-Gly-NMe-Phe-Gly-ol|Tyr-D-Ala-Gly-NMePhe-Gly-ol|(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]-N-methylacetamido}-N-(2-hydroxyethyl)-3-phenylpropanamide|4-phenylcyclohexane|Acetic acid, ester with 2,6-dimethyl-m-dioxan-4-ol|glyol|H-Tyr-D-Ala-Gly-N-Me-Phe-Glycinol|Enkephalin, Ala(2)-MePhe(4)-Gly-ol(5)-|(2S)-2-amino-N-[(1R)-2-[[2-[[(1S)-1-benzyl-2-(2-hydroxyethylamino)-2-oxo-ethyl]-methyl-amino]-2-oxo-ethyl]amino]-1-methyl-2-oxo-ethyl]-3-(4-hydroxyphenyl)propanamide|Enkephalin, alanyl(2)-methylphenylalanyl(4)-glycine(5)-|Mecamylamine hydrochloride (USP)|Tyr-D-Ala-Gly-MePhe-Gly-ol|Tyr-DAla-Gly-MePhe-Gly-ol|Tyr-D-Ala-Gly-MePhe-Gly(ol)|Dagol|DAMGO (TFA)|RX 783006

Storage

Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

概要仕様名前と識別子詳細データ Taxonomic Classification 3 D構造関連ターゲット（人間）関連ターゲット（非人間）作用メカニズム証明書（CoA、COO、BSE/TSEと分析図）化学的性質と物理的性質よくある質問と記事ソリューション計算機レビュー

概要

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

仕様

同義語

仕様と純度

Moligand™, ≥95%

生化学的・生理学的メカニズム

Potent and selective μ opioid receptor agonist (K i values are 2.0, >1000 and >1000 nM for opioid receptor subtypes μ, κ and δ, respectively). Partial central activity following systemic administration. Antinociceptive.

保管条件

Store at -20°C,Desiccated

入荷

Ice chest + Ice pads

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

等級

Moligand™

アクションタイプ

AGONIST

作用メカニズム

Agonist of κ receptor;Agonist of μ receptor

注

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

純度

≥95%

名前と識別子

パブケム・シド

528764085

カノニカル・スマイル

CC(C(=O)NCC(=O)N(C)C(CC1=CC=CC=C1)C(=O)NCCO)NC(=O)C(CC2=CC=C(C=C2)O)N

IUPAC Name

(2S)-2-amino-N-[(2R)-1-[[2-[[(2S)-1-(2-hydroxyethylamino)-1-oxo-3-phenylpropan-2-yl]-methylamino]-2-oxoethyl]amino]-1-oxopropan-2-yl]-3-(4-hydroxyphenyl)propanamide

InChIKey

HPZJMUBDEAMBFI-WTNAPCKOSA-N

INCHI

1S/C26H35N5O6/c1-17(30-25(36)21(27)14-19-8-10-20(33)11-9-19)24(35)29-16-23(34)31(2)22(26(37)28-12-13-32)15-18-6-4-3-5-7-18/h3-11,17,21-22,32-33H,12-16,27H2,1-2H3,(H,28,37)(H,29,35)(H,30,36)/t17-,21+,22+/m1/s1

異性体SMILES

C[C@H](C(=O)NCC(=O)N(C)[C@@H](CC1=CC=CC=C1)C(=O)NCCO)NC(=O)[C@H](CC2=CC=C(C=C2)O)N

分子量

513.59

Reaxy-Rn

25226561

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=25226561&ln=

詳細データ

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organic acids and derivatives
  - 分類 Carboxylic acids and derivatives
    - Subclass Amino acids, peptides, and analogues
      - Level5 Peptides
        Level6 Oligopeptides

Kingdom	Organic compounds
Superclass	Organic acids and derivatives
分類	Carboxylic acids and derivatives
Subclass	Amino acids, peptides, and analogues
Intermediate Tree Nodes	Peptides
Direct Parent	Oligopeptides
Alternative Parents	Tyrosine and derivatives Phenylalanine and derivatives N-acyl-alpha amino acids and derivatives Alpha amino acid amides Alanine and derivatives Amphetamines and derivatives N-acylethanolamines 1-hydroxy-2-unsubstituted benzenoids Aralkylamines Fatty amides Tertiary carboxylic acid amides Secondary carboxylic acid amides Primary alcohols Organopnictogen compounds Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds
Molecular Framework	Aromatic homomonocyclic compounds
Substituents	Alpha-oligopeptide - Tyrosine or derivatives - Phenylalanine or derivatives - N-acyl-alpha amino acid or derivatives - Alpha-amino acid amide - Alanine or derivatives - N-substituted-alpha-amino acid - Alpha-amino acid or derivatives - Amphetamine or derivatives - N-acylethanolamine - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Aralkylamine - Fatty acyl - Benzenoid - Monocyclic benzene moiety - Fatty amide - Tertiary carboxylic acid amide - Secondary carboxylic acid amide - Amino acid or derivatives - Carboxamide group - Alkanolamine - Primary amine - Primary aliphatic amine - Organic oxide - Hydrocarbon derivative - Carbonyl group - Organonitrogen compound - Organopnictogen compound - Organooxygen compound - Amine - Organic oxygen compound - Alcohol - Primary alcohol - Organic nitrogen compound - Aromatic homomonocyclic compound
説明	This compound belongs to the class of organic compounds known as oligopeptides. These are organic compounds containing a sequence of between three and ten alpha-amino acids joined by peptide bonds.
External Descriptors	peptide
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

3 D構造

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レビュー

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Lot Number	Certificate Type	日付	商品
K2110375	Certificate of Analysis	Jun 11, 2026	D275414
K2110376	Certificate of Analysis	Jun 11, 2026	D275414
K2111140	Certificate of Analysis	Jun 11, 2026	D275414
K2111141	Certificate of Analysis	Jun 11, 2026	D275414

溶解度	Soluble in water to 1 mg/ml
分子量	513.600 g/mol
XLogP3	0.200
Hydrogen Bond Donor Count	6
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	13
Exact Mass	513.259 Da
Monoisotopic Mass	513.259 Da
Topological Polar Surface Area	174.000 Å²
Heavy Atom Count	37
Formal Charge	0
Complexity	752.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	3
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1